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Articles Published Processes
9/7/2017 8:51:55 AM | Browse: 1264 | Download: 2530
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Received |
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2017-03-02 08:30 |
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Peer-Review Started |
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2017-03-03 19:24 |
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To Make the First Decision |
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2017-04-21 10:04 |
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Return for Revision |
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2017-04-27 20:27 |
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Revised |
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2017-05-30 08:29 |
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Second Decision |
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2017-07-06 07:17 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-07-12 06:07 |
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Articles in Press |
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2017-07-12 06:07 |
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Publication Fee Transferred |
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2017-07-30 06:31 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-09-04 02:58 |
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Publish the Manuscript Online |
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2017-09-07 08:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Morten L Halling, Jens Kjeldsen, Torben Knudsen, Jan Nielsen and Lars Koch-Hansen |
| Funding Agency and Grant Number |
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| Corresponding Author |
Morten L Halling, MD, Department of Gastroenterology and Hepatology, Hospital of Southwest Jutland, Medicinsk Gastroenterologisk Afdeling, Sydvestjysk Sygehus, Finsensgade 35, 6700 Esbjerg, Denmark. mortenhalling@gmail.com |
| Key Words |
Immune mediated diseases; Ulcerative colitis; Risk; Prevalence; Registry; Chronic inflammatory diseases; Autoimmune diseases; Inflammatory bowel disease; Crohn’s disease; Extraintestinal manifestations |
| Core Tip |
Essential to inflammatory bowel disease (IBD) pathogenesis are environmental factors, altered gut microbiota and genetic susceptibility. The latter causing impairment of barrier function, autophagy, and Th1, 2 and 17 cell responses. Interestingly, these mechanisms are also thought important in other immune mediated diseases, as is the overlap of susceptibility genes. Besides the classic extraintestinal manifestations, we found a variety of immune mediated diseases to be more frequent in individuals with IBD. Physicians should be aware of this when treating these patients. Furthermore, these findings support the hypothesis that immune mediated diseases may have overlapping pathogeneses. Thus, understanding IBD might help us understand other immune mediated diseases and vice versa. |
| Publish Date |
2017-09-07 08:51 |
| Citation |
Halling ML, Kjeldsen J, Knudsen T, Nielsen J, Koch Hansen L. Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases. World J Gastroenterol 2017; 23(33): 6137-6146 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i33/6137.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i33.6137 |
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