BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/7/2017 11:41:16 AM | Browse: 1367 | Download: 2663
 |
Received |
|
2017-03-14 10:32 |
|
Peer-Review Started |
|
2017-03-15 16:36 |
 |
First Decision by Editorial Office Director |
|
|
|
Return for Revision |
|
2017-03-31 16:17 |
|
Revised |
|
2017-04-04 20:26 |
|
Publication Fee Transferred |
|
2017-05-18 04:27 |
|
Second Decision by Editor |
|
2017-04-27 18:16 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2017-05-04 18:37 |
|
Articles in Press |
|
2017-05-04 18:37 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2017-06-24 15:02 |
|
Publish the Manuscript Online |
|
2017-07-07 11:41 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Seung Kak Shin, Jae Hee Cho, Eui Joo Kim, Eun-Kyung Kim, Dong Kyun Park, Kwang An Kwon, Jun-Won Chung, Kyoung Oh Kim and Yoon Jae Kim |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science, ICT and Future Planning |
2014R1A1A1A05008202 |
|
| Corresponding Author |
Yoon Jae Kim, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Gachon University Gil Medical Center, 21, Namdong-daero 774 beon-gil, Namdong-gu, Incheon 21565, South Korea. yoonmed@gachon.ac.kr |
| Key Words |
Oxidative stress; Inflammatory bowel disease; Rosuvastatin; Apoptosis |
| Core Tip |
Oxidative stress in the intestinal tract is considered a major factor that contributes to the pathogenesis and progression of inflammatory bowel disease (IBD). We report that rosuvastatin has the antioxidant, anti-inflammatory and anti-apoptotic effects in dextran sulfate sodium (DSS)-induced colitis mice. We assume the possibility of anti-inflammatory effects of rosuvastatin through the regulation of oxidative stress, and first describe the anti-apoptotic effects of rosuvastatin in a DSS-induced colitis model. Therefore, rosuvastatin might be a candidate anti-inflammatory drug in patients with IBD. |
| Publish Date |
2017-07-07 11:41 |
| Citation |
Shin SK, Cho JH, Kim EJ, Kim EK, Park DK, Kwon KA, Chung JW, Kim KO, Kim YJ. Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model. World J Gastroenterol 2017; 23(25): 4559-4568 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i25/4559.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i25.4559 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
