Publication Name	World Journal of Gastroenterology
Manuscript ID	3403
Country	Japan

Received	2013-04-27 16:10
Peer-Review Started	2013-04-28 20:20
First Decision by Editorial Office Director
Return for Revision	2013-06-02 19:49
Revised	2013-06-28 12:17
Publication Fee Transferred
Second Decision by Editor	2013-08-06 08:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-08-06 11:50
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-09-23 20:53
Publish the Manuscript Online	2013-10-18 17:02

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Autobiography
Article Title	Incidence and characteristics of HBV reactivation in hematological malignant patients in south Egypt
Manuscript Source	Invited Manuscript
All Author List	Abeer Elkady, Sahar Aboulfotuh, Elsayed Mostafa Ali, Douaa Sayed, Nashwa M Abdel-Aziz, Amany M Ali, Shuko Murakami, Sayuki Iijima and Yasuhito Tanaka
Funding Agency and Grant Number	Funding Agency Grant Number Grant for National Center For Global Health and Medicine 22A-9 Grant-in-Aid form Japan Society for the Promotion of Science (JSPS) Fellows 21.09355 Grant-in-Aid form the Ministry of Health, Labour and Welfare of Japan
Corresponding Author	Yasuhito Tanaka, MD, PhD, Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan. ytanaka@med.nagoya-cu.ac.jp
Key Words	Hepatitis B virus; Occult infection; Reactivation; Hepatitis B surface antigen
Core Tip	The study aimed to investigate characteristics of hepatitis B virus (HBV) implicated in HBV reactivation in patients with hematological malignancies receiving immunosuppressive therapy in Egypt. Fifty-three hepatitis B surface antigen (HBsAg)-negative patients treated with chemotherapy were included in the study. The incidence of HBV reactivation was 9.4% among the studied cohort, and all of the affected individuals were positive for HBsAg as well as antibodies to the hepatitis B core antigen. The present study provides further evidence via molecular evolutionary analysis of the development of HBV reactivation from an occult HBV infection. Past infection with HBV is a risk factor for HBV reactivation in Egypt. Mandatory antibodies to the core antigen screening prior to chemotherapy in patients with hematological malignancies is suggested.
Publish Date	2013-10-18 17:02
Citation	Elkady A, Aboulfotuh S, Ali EM, Sayed D, Abdel-Aziz NM, Ali AM, Murakami S, Iijima S, Tanaka Y. Incidence and characteristics of HBV reactivation in hematological malignant patients in south Egypt. World J Gastroenterol 2013; 19(37): 6214-6220
URL	http://www.wjgnet.com/1007-9327/full/v19/i37/6214.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i37.6214

Full Article (PDF)	WJG-19-6214.pdf
Manuscript File	3403-Review.doc
Answering Reviewers	3403-Answering reviewers.pdf
Copyright License Agreement	3403-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3403-Language certificate.pdf
Peer-review Report	3403-Peer review(s).pdf
Scientific Editor Work List	3403-Scientific editor work list.doc