Publication Name	World Journal of Gastroenterology
Manuscript ID	34036
Country	China

Received	2017-03-23 17:11
Peer-Review Started	2017-03-23 17:21
To Make the First Decision	2017-04-10 14:46
Return for Revision	2017-04-11 14:27
Revised	2017-04-15 10:53
Second Decision	2017-05-27 01:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-06-01 06:35
Articles in Press	2017-06-01 06:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2017-06-20 02:52
Typeset the Manuscript	2017-07-14 03:01
Publish the Manuscript Online	2017-07-28 08:16

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article; it was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Editorial
Article Title	Precision medicine: In need of guidance and surveillance
Manuscript Source	Invited Manuscript
All Author List	Jian-Zhen Lin, Jun-Yu Long, An-Qiang Wang, Ying Zheng and Hai-Tao Zhao
Funding Agency and Grant Number	Funding Agency Grant Number International Science and Technology Cooperation Projects 2016YFE0107100 International Science and Technology Cooperation Projects 2015DFA30650 International Science and Technology Cooperation Projects 2010DFB33720 Capital Special Research Project for Health Development (2014-2-4012), Capital Research Project for The Characteristics Clinical Application Z151100004015170 Beijing Nature Science Foundation for Young Scholars Project 7164293 Program for New Century Excellent Talents in University NCET-11-0288 Capital Special Research Project for Health Development 2014-2-4012
Corresponding Author	Hai-Tao Zhao, MD, PhD, Professor, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 9 Dongdansantiao, Dongcheng District, Beijing 100730, China. zhaoht@pumch.cn
Key Words	Precision medicine; Clinical translation; Development; Targeted therapy; Immunotherapy
Core Tip	Precision medicine aims toward accurate, efficient and effective diagnostic testing and precise treatment. Emerging techniques and therapeutic drugs based on molecular profiling and genomic characteristics will help achieve that goal. Next-generation sequencing is the most frequently used methodology for precision medicine applications; however, proteomics and metabolomics tests are growing in accuracy and ease of use. In terms of applications and outcomes, the benefits conferred by precision medicine are currently insufficient. Present development of precision medicine lacks order. Therefore, precision medicine needs strong support to develop, and a directed momentum is required. We suggest three kinds of impetus (research, application and collaboration impetus) for such directed momentum toward promoting precision medicine and accelerating its clinical translation and application.
Publish Date	2017-07-28 08:16
Citation	Lin JZ, Long JY, Wang AQ, Zheng Y, Zhao HT. Precision medicine: In need of guidance and surveillance. World J Gastroenterol 2017; 23(28): 5045-5050
URL	http://www.wjgnet.com/1007-9327/full/v23/i28/5045.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i28.5045

Full Article (PDF)	WJG-23-5045.pdf
Full Article (Word)	WJG-23-5045.doc
Manuscript File	34036-Review.docx
Answering Reviewers	34036-Answering reviewers.pdf
Audio Core Tip	34036-Audio core tip.WAV
Conflict-of-Interest Disclosure Form	34036_conflict of interest.pdf
Copyright License Agreement	34036-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	34036_grant form.pdf
Non-Native Speakers of English Editing Certificate	34036-Grant application form(s).pdf
Peer-review Report	34036-Peer-review(s).pdf
Scientific Misconduct Check	34036-Scientific misconduct check.pdf
Scientific Editor Work List	34036-Scientific editor work list.pdf