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10/27/2017 12:23:13 AM | Browse: 463 | Download: 421
Publication Name World Journal of Hepatology
Manuscript ID 34072
Country/Territory Serbia
2017-03-25 13:34
Peer-Review Started
2017-03-28 18:27
To Make the First Decision
2017-06-14 01:07
Return for Revision
2017-06-30 12:58
2017-08-16 12:26
Second Decision
2017-09-08 01:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-18 02:03
Articles in Press
2017-09-18 02:03
Publication Fee Transferred
2017-10-02 17:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-10-25 01:50
Publish the Manuscript Online
2017-10-27 00:23
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Liver cystic echinococcosis and human host immune and autoimmune follow-up: A review
Manuscript Source Unsolicited Manuscript
All Author List Nikica M Grubor, Katica D Jovanova-Nesic and Yehuda Shoenfeld
Funding Agency and Grant Number
Corresponding author Katica D Jovanova-Nesic, PhD, Immunology Research Center, Institute of Virology, Vaccine and Sera-Torlak, Vojvode Stepe 458, Belgrade 11221, Serbia. jovanok@afrodita.rcub.bg.ac.rs
Key Words Lymphocytes; Dendritic cells; Immunity; Autoimmunity; Cytokines; Echinococcus granulosus
Core Tip The most common location of a hydatid echinococcal cyst is in the liver. The survival of Echinococcus within host tissues, despite the development of specific antibodies, is possible due to specific immunomodulation induced by parasites. Perpetual survival of parasites indicating multi-level systematic evasion against host protective reaction to persist their growth and spreading. Complement modulation, a metabolic adaptation to the host microenvironment, plentiful thermostable immunogenic antigen B in the cystic fluid, and induction of CD4+CD8+FOXP3+ T cells allows the persistence of the parasites. Parasites influence dendritic cell (DC) maturation and impair activation by toll-like receptor. It seems that DC-parasite interaction is pivotal in triggering and regulating parasite induced immunity.
Publish Date 2017-10-27 00:23
Citation Grubor NM, Jovanova-Nesic KD, Shoenfeld Y. Liver cystic echinococcosis and human host immune and autoimmune follow-up: A review. World J Hepatol 2017; 9(30): 1176-1189
Url http://www.wjgnet.com/1948-5182/full/v9/i30/1176.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i30.1176
Full Article (PDF) WJH-9-1176.pdf
Full Article (Word) WJH-9-1176.doc
Manuscript File 34072-Review.docx
Answering Reviewers 34072-Answering-Reviewers-revision_1751.docx
Audio Core Tip 34072-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34072-Conflict-of-Interest-Statement-revision_2228.pdf
Copyright License Agreement 34072-Copyright-Assignment-revision_1955.pdf
Non-Native Speakers of English Editing Certificate 34072-Non-Native-Speakers-of-English-revision_2535.pdf
Supplementary Material 34072-Supplementary-Material-revision.pptx
Peer-review Report 34072-Peer-review(s).pdf
Scientific Misconduct Check 34072-Scientific misconduct check.pdf
Scientific Editor Work List 34072-Scientific editor work list.pdf