Publication Name	World Journal of Gastroenterology
Manuscript ID	34090
Country	China

Received	2017-03-27 08:54
Peer-Review Started	2017-03-29 15:56
First Decision by Editorial Office Director
Return for Revision	2017-05-03 10:26
Revised	2017-05-29 23:58
Publication Fee Transferred	2017-08-16 14:11
Second Decision by Editor	2017-06-27 00:40
Second Decision by Editor-in-Chief	2017-06-29 03:03
Final Decision by Editorial Office Director	2017-08-08 17:04
Articles in Press	2017-08-08 17:04
Edit the Manuscript by Language Editor	2017-09-25 05:28
Typeset the Manuscript	2017-12-05 09:05
Publish the Manuscript Online	2017-12-12 08:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative work on different terms, provided the original work is properly cited and use is non-commercial. See: http://creativecommons. org/licenses/by-nc/ 4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	In vivo hepatic differentiation potential of human umbilical cord-derived mesenchymal stem cells: Therapeutic effect on liver fibrosis/cirrhosis
Manuscript Source	Unsolicited Manuscript
All Author List	Guo-Zun Zhang, Hui-Cong Sun, Li-Bo Zheng, Jin-Bo Guo and Xiao-Lan Zhang
Funding Agency and Grant Number
Corresponding Author	Xiao-Lan Zhang, MD, PhD, Professor, Department of Gastroenterology, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. xiaolanzh@hb2h.com
Key Words	Liver fibrosis/cirrhosis; Mesenchymal stem cells; Collagen metabolism; Hepatocyte; Differentiation
Core Tip	Transplanted human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could differentiate into hepatocytes in vivo, thereby reducing the activation state of hepatic stellate cells, decreasing collagen deposition, and enhancing extracellular matrix remodeling in liver cirrhosis. hUC-MSCs play an important role in treating liver fibrosis and cirrhosis.
Publish Date	2017-12-12 08:34
Citation	Zhang GZ, Sun HC, Zheng LB, Guo JB, Zhang XL. In vivo hepatic differentiation potential of human umbilical cord-derived mesenchymal stem cells: Therapeutic effect on liver fibrosis/cirrhosis. World J Gastroenterol 2017; 23(46): 8152-8168
URL	http://www.wjgnet.com/1007-9327/full/v23/i46/8152.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i46.8152

Full Article (PDF)	WJG-23-8152.pdf
Full Article (Word)	WJG-23-8152.doc
Manuscript File	34090-Review.doc
Answering Reviewers	34090-Answering reviewers.pdf
Audio Core Tip	34090-Audio core tip.mp3
Biostatistics Review Certificate	34090-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	34090-Conflict-of-interest statement.pdf
Copyright License Agreement	34090-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	34090-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	34090-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	34090-Language certificate.pdf
Peer-review Report	34090-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	34090-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	34090-Scientific misconduct check.pdf
Scientific Editor Work List	34090-Scientific editor work list.pdf