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Articles Published Processes
12/12/2017 8:34:13 AM | Browse: 1106 | Download: 1790
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Received |
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2017-03-27 08:54 |
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Peer-Review Started |
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2017-03-29 15:56 |
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To Make the First Decision |
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2017-05-03 10:26 |
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Return for Revision |
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2017-05-03 10:26 |
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Revised |
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2017-05-29 23:58 |
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Second Decision |
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2017-06-27 00:40 |
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Accepted by Journal Editor-in-Chief |
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2017-06-29 03:03 |
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Accepted by Executive Editor-in-Chief |
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2017-08-08 17:04 |
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Articles in Press |
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2017-08-08 17:04 |
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Publication Fee Transferred |
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2017-08-16 14:11 |
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Edit the Manuscript by Language Editor |
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2017-09-25 05:28 |
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Typeset the Manuscript |
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2017-12-05 09:05 |
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Publish the Manuscript Online |
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2017-12-12 08:34 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative work on different terms, provided the original work is properly cited and use is non-commercial. See: http://creativecommons. org/licenses/by-nc/ 4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
In vivo hepatic differentiation potential of human umbilical cord-derived mesenchymal stem cells: Therapeutic effect on liver fibrosis/cirrhosis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Guo-Zun Zhang, Hui-Cong Sun, Li-Bo Zheng, Jin-Bo Guo and Xiao-Lan Zhang |
Funding Agency and Grant Number |
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Corresponding Author |
Xiao-Lan Zhang, MD, PhD, Professor, Department of Gastroenterology, The Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. xiaolanzh@hb2h.com |
Key Words |
Liver fibrosis/cirrhosis; Mesenchymal stem cells; Collagen metabolism; Hepatocyte; Differentiation |
Core Tip |
Transplanted human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could differentiate into hepatocytes in vivo, thereby reducing the activation state of hepatic stellate cells, decreasing collagen deposition, and enhancing extracellular matrix remodeling in liver cirrhosis. hUC-MSCs play an important role in treating liver fibrosis and cirrhosis. |
Publish Date |
2017-12-12 08:34 |
Citation |
Zhang GZ, Sun HC, Zheng LB, Guo JB, Zhang XL. In vivo hepatic differentiation potential of human umbilical cord-derived mesenchymal stem cells: Therapeutic effect on liver fibrosis/cirrhosis. World J Gastroenterol 2017; 23(46): 8152-8168 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i46/8152.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i46.8152 |
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