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Articles Published Processes
8/18/2017 2:46:28 AM | Browse: 922 | Download: 1122
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Received |
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2017-03-28 14:17 |
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Peer-Review Started |
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2017-03-29 17:17 |
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To Make the First Decision |
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2017-04-17 09:17 |
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Return for Revision |
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2017-04-18 15:26 |
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Revised |
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2017-05-17 14:25 |
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Second Decision |
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2017-06-02 00:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-06-13 05:12 |
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Articles in Press |
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2017-06-13 05:12 |
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Publication Fee Transferred |
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2017-07-28 02:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-08-15 09:27 |
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Publish the Manuscript Online |
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2017-08-18 02:46 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Minireviews |
| Article Title |
Multifunctional biomimetic spinal cord: New approach to repair spinal cord injuries
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Liu, Qian Li, Bin Zhang, De-Xiang Ban and Shi-Qing Feng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81330042 |
| Special Program for Sino-Russian Joint, Research Sponsored by the Ministry of Science and Technology, China |
2014DFR31210 |
| Key Program Sponsored by the Tianjin Science and Technology Committee, China |
13RCGFSY19000 14ZCZDSY00044 |
| National Natural Science Foundation of China |
81201399 |
| National Natural Science Foundation of China |
81301544 |
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| Corresponding Author |
Shi-Qing Feng, PhD, Department of Orthopedic Surgery, Tianjin Medical University General Hospital, No. 154, Anshan Road, Heping District, Tianjin 300052, China. sqfeng@tmu.edu.cn |
| Key Words |
Spinal cord injuries; Glial scar; Hydrogel materials; Basic fibroblast growth factor; Acellular scaffold |
| Core Tip |
Traumatic spinal cord injury often leads to serious consequences and also adds great burden to families and society. Usually people believe that the regeneration of lost tissue is limited after central nervous system injury. Due to these reasons, we would like to provide a new bionic spinal cord to reduce the negative effect of glial scar on nerve regeneration. We design biomimetic spinal cord by the combination of basic fibroblast growth factor modified thermosensitive hydrogel and acellular spinal cord scaffold, which is conducive to the designation of a three-dimensional composite scaffold more suitable for cell growth, and corresponding mechanical properties and biodegradability more close to the structure of normal spinal cord. |
| Publish Date |
2017-08-18 02:46 |
| Citation |
Liu Y, Li Q, Zhang B, Ban DX, Feng SQ. Multifunctional biomimetic spinal cord: New approach to repair spinal cord injuries. World J Exp Med 2017; 7(3): 78-83 |
| URL |
http://www.wjgnet.com/2220-315X/full/v7/i3/78.htm |
| DOI |
http://dx.doi.org/10.5493/wjem.v7.i3.78 |
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