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Articles Published Processes
9/7/2017 8:51:55 AM | Browse: 1487 | Download: 2528
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Received |
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2017-05-08 09:32 |
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Peer-Review Started |
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2017-05-08 17:14 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2017-06-07 00:15 |
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Revised |
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2017-07-05 18:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2017-08-01 02:35 |
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Second Decision by Editor-in-Chief |
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2017-08-02 15:31 |
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Final Decision by Editorial Office Director |
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2017-08-08 17:01 |
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Articles in Press |
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2017-08-08 17:01 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-09-04 02:56 |
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Publish the Manuscript Online |
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2017-09-07 08:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Helminths as an alternative therapy for intestinal diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Aytan Miranda Sipahi and Daniel Machado Baptista |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Aytan Miranda Sipahi, MD, PhD, LIM 07-Laboratory of Experimental Clinical Gastroenterology, Department of Gastroenterology and Hepatology, Clínicas Hospital of University of São Paulo-HCFMUSP and, School of Medicine at the University of São Paulo, São Paulo 04023-062, Brazil. |
| Key Words |
Helminths; Strongyloidiasis; Immunology; Inflammation; Inflammatory bowel diseases; Intestinal diseases; Intestinal permeability; Celiac disease |
| Core Tip |
Inflammatory bowel disease and celiac disease are immune-mediated pathologies that remain a treatment challenge for gastroenterologists. Despite the recent introduction of novel therapies, notably biological agents and newer management strategies, there are still many patients who do not respond, or have a poor response to current treatments. Helminth therapy seems a promising pathway to newer drugs, because it has been proven to alter intestinal permeability, altering the host’s immune response to a Type 2 cytokine-mediated response in animal models and pre-clinical studies. This editorial aims to stimulate further research in this field, hoping for better care for our patients. |
| Publish Date |
2017-09-07 08:51 |
| Citation |
Sipahi AM, Baptista DM. Helminths as an alternative therapy for intestinal diseases. World J Gastroenterol 2017; 23(33): 6009-6015 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i33/6009.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i33.6009 |
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