Publication Name	World Journal of Respirology
Manuscript ID	34314
Country	Portugal

Received	2017-05-01 12:08
Peer-Review Started	2017-05-03 11:33
To Make the First Decision	2017-05-22 01:44
Return for Revision	2017-05-23 09:25
Revised	2017-06-05 12:50
Second Decision	2017-06-22 02:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-07-03 02:43
Articles in Press	2017-07-03 02:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-18 08:34
Publish the Manuscript Online	2017-07-21 02:55

ISSN	2218-6255 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Respiratory System
Manuscript Type	Frontier
Article Title	Is the determination of ctDNA a scientific “spy” that foresees cancer?
Manuscript Source	Invited Manuscript
All Author List	Joana Espiga de Macedo and Manuela Machado
ORCID	Author(s) ORCID Number Joana Espiga de Macedo http://orcid.org/0000-0002-9637-313X Manuela Machado http://orcid.org/0000-0003-2324-2435
Funding Agency and Grant Number
Corresponding Author	Joana Espiga de Macedo, MD, Consultant of Medical Oncology, Department of Medical Oncology of Centro Hospitalar de Entre Douro e Vouga, Rua Dr. Cândido de Pinho, 4520-211 Santa Maria Da Feira, Portugal. joana.macedo@chedv.min-saude.pt
Key Words	Tumour biopsies; Liquid biopsies; Circulating tumour DNA; Precision cancer medicine
Core Tip	With the increase development of molecular medicine we may further change our clinical rational to a precise cancer medicine rational way. Consequently, we may improve the quality of life of our patients, with less toxicity, more cost-effectiveness decisions and above all improve response rate and survival. Defining the complete genomic “picture” of all cancerous lesions, in the near future as a standard of care, will require all genetic information concerning each individual cancer.
Publish Date	2017-07-21 02:55
Citation	de Macedo JE, Machado M. Is the determination of ctDNA a scientific “spy” that foresees cancer? World J Respirol 2017; 7(2): 35-38
URL	http://www.wjgnet.com/2218-6255/full/v7/i2/35.htm
DOI	http://dx.doi.org/10.5320/wjr.v7.i2.35

Full Article (PDF)	WJR-7-35.pdf
Full Article (Word)	WJR-7-35.doc
Manuscript File	34314-Review.docx
Answering Reviewers	34314-Answering reviewers.pdf
Audio Core Tip	34314-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	34314-Conflict-of-interest statement.pdf
Copyright License Agreement	34314-Copyright assignment.pdf
Supplementary Material	34314_table SPY.docx
Peer-review Report	34314-Peer-review(s).pdf
Scientific Misconduct Check	34314-Scientific misconduct check.pdf
Scientific Editor Work List	34314-Scientific editor work list.pdf