| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Management of gastric mucosa-associated lymphoid tissue lymphoma in patients with extra copies of the MALT1 gene
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Masaya Iwamuro, Ryuta Takenaka, Masahiro Nakagawa, Yuki Moritou, Shunsuke Saito, Shinichiro Hori, Tomoki Inaba, Yoshinari Kawai, Tatsuya Toyokawa, Takehiro Tanaka, Tadashi Yoshino and Hiroyuki Okada |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Masaya Iwamuro, MD, PhD, Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-Ku, Okayama 700-8558, Japan. iwamuromasaya@yahoo.co.jp |
| Key Words |
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue; Gastric neoplasms; Esophagogastroduodenoscopy; t(11; 18) translocation; Trisomy 18 |
| Core Tip |
We subdivided and retrospectively reviewed 146 patients with gastric MALT lymphoma into patients without t(11;18) translocation or extra copies of MALT1 (Group A, n = 88, 60.3%), patients with t(11;18) translocation (Group B, n = 27, 18.5%), and patients with extra copies of MALT1 (Group C, n = 31, 21.2%). Groups A and C exhibited similar clinical characteristics. Helicobacter pylori eradication alone resulted in complete remission in approximately half the patients in Group A and Group C. Consequently, patients with extra copies of MALT1 could be treated similar to patients without t(11;18) translocation or extra copies of MALT1. |
| Publish Date |
2017-09-07 08:51 |
| Citation |
Iwamuro M, Takenaka R, Nakagawa M, Moritou Y, Saito S, Hori S, Inaba T, Kawai Y, Toyokawa T, Tanaka T, Yoshino T, Okada H. Management of gastric mucosa-associated lymphoid tissue lymphoma in patients with extra copies of the MALT1 gene. World J Gastroenterol 2017; 23(33): 6155-6163 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i33/6155.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i33.6155 |
