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Articles Published Processes
9/14/2017 3:13:08 AM | Browse: 1100 | Download: 1981
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Received |
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2017-05-08 09:14 |
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Peer-Review Started |
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2017-05-08 16:46 |
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To Make the First Decision |
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2017-06-22 01:02 |
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Return for Revision |
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2017-06-23 09:11 |
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Revised |
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2017-07-05 16:17 |
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Second Decision |
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2017-08-01 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-08-08 17:02 |
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Articles in Press |
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2017-08-08 17:02 |
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Publication Fee Transferred |
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2017-08-10 14:54 |
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Edit the Manuscript by Language Editor |
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2017-08-21 00:44 |
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Typeset the Manuscript |
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2017-09-04 11:44 |
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Publish the Manuscript Online |
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2017-09-14 03:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected b-y an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is prope-rly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Chemistry, Medicinal |
| Manuscript Type |
Basic Study |
| Article Title |
Dihydromyricetin-mediated inhibition of the Notch1 pathway induces apoptosis in QGY7701 and HepG2 hepatoma cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Cai-Jie Lu, Yi-Feng He, Wei-Zhuang Yuan, Li-Jun Xiang, Jian Zhang, Yan-Rui Liang, Juan Duan, Yun-He He and Ming-Yi Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Funds |
81041099 |
| Natural Science Foundation of Guangdong Province |
S2011010003750 |
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| Corresponding Author |
Ming-Yi Li, PhD, Professor, Laboratory of Hepatobiliary Surgery, Affiliated Hospital of Guangdong Medical University, No. 57 South Renmin Road, Zhanjiang 524001, Guangdong Province, China. limingyi62@163.com |
| Key Words |
Dihydromyricetin; Apoptosis; Hepatocellular carcinoma; Notch1 |
| Core Tip |
The novel findings of this study are that Notch1 is highly expressed in tumor cells with higher degrees of malignancy and proliferative activity, Notch1 is involved in the development of hepatocellular carcinoma (HCC) and may serve as a potential diagnostic marker for HCC. Dihydromyricetin can strongly induce apoptosis of the hepatic cancer cell lines QGY7701 and HepG2 by downregulating the expression of Notch1. |
| Publish Date |
2017-09-14 03:13 |
| Citation |
Lu CJ, He YF, Yuan WZ, Xiang LJ, Zhang J, Liang YR, Duan J, He YH, Li MY. Dihydromyricetin-mediated inhibition of the Notch1 pathway induces apoptosis in QGY7701 and HepG2 hepatoma cells. World J Gastroenterol 2017; 23(34): 6242-6251 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i34/6242.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i34.6242 |
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