Publication Name	World Journal of Gastroenterology
Manuscript ID	3461
Country	United States

Received	2013-05-01 13:49
Peer-Review Started	2013-05-03 13:42
To Make the First Decision	2013-07-26 18:34
Return for Revision	2013-08-09 10:18
Revised	2013-10-07 22:34
Second Decision	2013-10-14 09:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-10-14 13:25
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-03 19:52
Publish the Manuscript Online	2013-12-18 10:00

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus: A pilot ex-vivo study
Manuscript Source	Invited Manuscript
All Author List	Yutaka Tomizawa, Prasad G Iyer, Louis M Wongkeesong, Navtej S Buttar, Lori S Lutzke, Tsung-Teh Wu and Kenneth K Wang
Funding Agency and Grant Number
Corresponding Author	Kenneth K Wang, MD, Professor, Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, 1st Street SW, Rochester, MN 55905, United States. wang.kenneth@mayo.edu
Key Words	Endocytoscopy; Barrett's esophagus; Dysplasia; Esophageal adenocarcinoma; Interobserver agreement
Core Tip	The current gold standard for surveillance of esophageal adenocarcioma in Barretts's esophagus (BE) is endoscopic random biopsy and pathological diagnosis. Endocytoscopy (ECS) has the potential to provide a virtual histological diagnosis in vivo and in real-time. However, a major issue relates to that interpretation of cellular and nuclear images may be subject to similar interobserver variability associated with conventional histopathological diagnosis, and there have been no reliable classification systems for the endocytoscopic diagnosis. We presented the first study to investigate classification system of ECS in BE. This ex-vivo pilot study demonstrated acceptable diagnostic accuracy and excellent interobserver agreement.
Publish Date	2013-12-18 10:00
Citation	Tomizawa Y, Iyer PG, Wongkeesong LM, Buttar NS, Lutzke LS, Wu TT, Wang KK. Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett’s esophagus: A pilot ex-vivo study. World J Gastroenterol 2013; 19(46): 8652-8658
URL	http://www.wjgnet.com/1007-9327/full/v19/i46/8652.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i46.8652

Full Article (PDF)	WJG-19-8652.pdf
Manuscript File	3461-Review.doc
Answering Reviewers	3461-Answering Reviewers-1.pdf
Copyright License Agreement	3461-Copyright assignment.pdf
Peer-review Report	3461-Peer review(s).pdf
Scientific Editor Work List	3461-Scientific editor work list.doc