Publication Name	World Journal of Gastroenterology
Manuscript ID	34625
Country	United States

Received	2017-05-11 08:32
Peer-Review Started	2017-05-12 20:48
To Make the First Decision	2017-06-05 00:25
Return for Revision	2017-06-11 11:02
Revised	2017-07-07 22:29
Second Decision	2017-07-28 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-08-02 07:13
Articles in Press	2017-08-02 07:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-09-04 02:43
Publish the Manuscript Online	2017-09-07 08:51

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis
Manuscript Source	Invited Manuscript
All Author List	Derrick D Eichele and Kusum K Kharbanda
ORCID	Author(s) ORCID Number Derrick D Eichele http://orcid.org/0000000218403241 Kusum K Kharbanda http://orcid.org/0000000177598889
Funding Agency and Grant Number	Funding Agency Grant Number Department of Veterans Affairs, Office of Research and Development (Biomedical Laboratory Research and Development) BX001155
Corresponding Author	Kusum K Kharbanda, PhD, Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service (151), 4101 Woolworth Avenue, Omaha, NE 68105, United States. kkharbanda@unmc.edu
Key Words	Dextran sodium sulfate; Experimental colitis; Inflammatory bowel disease; Pathogenesis; Intestinal barrier
Core Tip	In the last few decades the proliferation of research in experimental colitis models of inflammatory bowel diseases (IBD) has had profound effects in our understanding of human IBD pathophysiology as well as to exploit potential therapeutic avenues outside of immunologic therapy. The dextran sodium sulfate colitis model, through its rapidity, simplicity, reproducibility and controllability has been instrumental in our understanding of intestinal barrier function through the dysregulation of mucin, interaction with the intestinal microbiome and metabolome.
Publish Date	2017-09-07 08:51
Citation	Eichele DD, Kharbanda KK. Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis. World J Gastroenterol 2017; 23(33): 6016-6029
URL	http://www.wjgnet.com/1007-9327/full/v23/i33/6016.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i33.6016

Full Article (PDF)	WJG-23-6016.pdf
Full Article (Word)	WJG-23-6016.doc
Manuscript File	34625-Review.docx
Answering Reviewers	34625-Answering reviewers.pdf
Audio Core Tip	34625-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	34625-Conflict-of-interest statement.pdf
Copyright License Agreement	34625-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	34625-Grant application form(s).pdf
Peer-review Report	34625-Peer-review(s).pdf
Scientific Misconduct Check	34625-Scientific misconduct check.pdf
Scientific Editor Work List	34625-Scientific editor work list.pdf