Publication Name	World Journal of Hepatology
Manuscript ID	3463
Country	Italy

Received	2013-05-01 13:59
Peer-Review Started	2013-05-03 14:16
To Make the First Decision	2013-05-28 12:03
Return for Revision	2013-05-28 17:24
Revised	2013-07-19 23:54
Second Decision	2013-08-16 19:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-16 23:22
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-09-03 09:22
Publish the Manuscript Online	2013-10-01 17:51

ISSN	1948-5182 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Autobiography
Article Title	Changes of liver fat content and transaminases in obese children after 12-mo nutritional intervention
Manuscript Source	Invited Manuscript
All Author List	Elvira Verduci, Carlo Pozzato, Giuseppe Banderali, Giovanni Radaelli, Chiara Arrizza, Antonio Rovere, Enrica Riva and Marcello Giovannini
Funding Agency and Grant Number
Corresponding Author	Elvira Verduci, PhD, Department of Pediatrics, San Paolo Hospital, University of Milan, Via A Di Rudinì 8, 20142 Milan, Italy. elvira.verduci@unimi.it
Key Words	Nonalcoholic fatty liver disease; Childhood obesity; Serum transaminases; Magnetic resonance imaging; Nutritional intervention
Core Tip	In our study we demonstrate that in obese children longitudinal change in liver fat content evaluated on magnetic resonance imaging is associated with change in serum transaminases and more weakly also with changes in triglyceridemia and apolipoproteins, after a nutritional intervention based on normocaloric balanced diet. Furthemore this is the first study purposely designed to evaluate in obese children whether any relationship may exist of longitudinal changes in liver fat content with changes in liver biochemical parameters These findings may suggest novelty in clinical monitoring nonalcoholic fatty liver disease severity in childhood obesity.
Publish Date	2013-10-01 17:51
Citation	Verduci E, Pozzato C, Banderali G, Radaelli G, Arrizza C, Rovere A, Riva E, Giovannini M. Changes of liver fat content and transaminases in obese children after 12-mo nutritional intervention. World J Hepatol 2013; 5(9): 505-512
URL	http://www.wjgnet.com/1948-5182/full/v5/i9/505.htm
DOI	http://dx.doi.org/10.4254/wjh.v5.i9.505

Full Article (PDF)	WJH-5-505.pdf
Manuscript File	3463-Review.doc
Answering Reviewers	3463-Answering reviewers.pdf
Copyright License Agreement	3463-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	comitato etico (1).pdf
Peer-review Report	3463-Peer review(s).pdf
Scientific Editor Work List	3463-Scientific editor work list.doc