Publication Name	World Journal of Gastroenterology
Manuscript ID	34659
Country	Ireland

Received	2017-05-16 03:19
Peer-Review Started	2017-05-18 01:09
To Make the First Decision	2017-06-22 00:39
Return for Revision	2017-06-23 10:36
Revised	2017-07-07 14:59
Second Decision	2017-08-02 00:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-08-08 05:59
Articles in Press	2017-08-08 05:59
Publication Fee Transferred	2017-09-29 05:29
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-10-31 03:46
Publish the Manuscript Online	2017-11-05 00:48

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine
Manuscript Source	Unsolicited Manuscript
All Author List	Finbarr O'Sullivan, Joanne Keenan, Sinead Aherne, Fiona O'Neill, Colin Clarke, Michael Henry, Paula Meleady, Laura Breen, Niall Barron, Martin Clynes, Karina Horgan, Padraig Doolan and Richard Murphy
ORCID	Author(s) ORCID Number Finbarr O'Sullivan http://orcid.org/0000-0003-1238-5721 Joanne Keenan http://orcid.org/0000-0003-0047-4268 Sinead Aherne http://orcid.org/0000-0003-4609-1633 Fiona O'Neill http://orcid.org/0000-0002-6935-5171 Colin Clarke http://orcid.org/0000-0003-2817-9527 Michael Henry http://orcid.org/0000-0001-5312-4961 Paula Meleady http://orcid.org/0000-0001-5306-310X Laura Breen http://orcid.org/0000-0001-5146-9333 Niall Barron http://orcid.org/0000-0003-4602-326X Martin Clynes http://orcid.org/0000-0002-3093-8185 Karina Horgan http://orcid.org/0000-0002-2251-8391 Padraig Doolan http://orcid.org/0000-0001-7401-4622 Richard Murphy http://orcid.org/0000-0002-4143-7431
Funding Agency and Grant Number	Funding Agency Grant Number Strategic Alliance Programme between Alltech and DCU in part
Corresponding Author	Finbarr O'Sullivan, PhD, Research Fellow, National Institute for Cellular Biotechnology, Dublin City Univeristy, Dublin D09 W6Y4, Ireland. finbarr.osullivan@dcu.ie
Key Words	Caco-2; HT-29; Microarray; Proteomics; miRNA; Targetscan; Gene ontology
Core Tip	Unique triomics analysis of Caco-2 and HT-29, two commonly used in vitro cell lines models of the intestine, was conducted. This analysis not only provided data on differentially expressed mRNAs, miRNAs and proteins but also allowed the identification of miRNA-regulated proteins differentially expressed between these two cell lines.
Publish Date	2017-11-05 00:48
Citation	O’Sullivan F, Keenan J, Aherne S, O’Neill F, Clarke C, Henry M, Meleady P, Breen L, Barron N, Clynes M, Horgan K, Doolan P, Murphy R. Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine. World J Gastroenterol 2017; 23(41): 7369-7386
URL	http://www.wjgnet.com/1007-9327/full/v23/i41/7369.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i41.7369

Full Article (PDF)	WJG-23-7369.pdf
Full Article (Word)	WJG-23-7369.doc
Manuscript File	34659-Review.docx
Answering Reviewers	34659-Answering reviewers.pdf
Audio Core Tip	34659-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	34659-Conflict-of-interest statement.pdf
Copyright License Agreement	34659-Copyright assignment.pdf
Supplementary Material	34659-Supplementary material.xlsx
Peer-review Report	34659-Peer-review(s).pdf
Scientific Misconduct Check	34659-Scientific misconduct check.pdf
Scientific Editor Work List	34659-Scientific editor work list.pdf