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Articles Published Processes
12/7/2017 10:00:55 AM | Browse: 1016 | Download: 1360
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Received |
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2017-05-15 01:36 |
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Peer-Review Started |
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2017-05-17 07:17 |
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To Make the First Decision |
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2017-06-14 00:47 |
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Return for Revision |
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2017-06-16 06:03 |
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Revised |
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2017-10-26 03:23 |
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Second Decision |
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2017-11-06 08:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-11-10 18:33 |
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Articles in Press |
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2017-11-10 18:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-12-06 07:10 |
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Publish the Manuscript Online |
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2017-12-07 10:00 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Case Report |
| Article Title |
Do you want to participate in a clinical study as a healthy control? - Risk or benefit?
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hanna Giessen, Christian A Nebiker, Matthias Bruehlmeier, Stefan Spreitzer, Beat Mueller and Philipp Schuetz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Philipp Schuetz, MD, Professor, Department of Internal Medicine, Kantonsspital Aarau, Tellstrasse 1, Aarau 5000, Switzerland. philipp.schuetz@ksa.ch |
| Key Words |
Medullary thyroid cancer; Procalcitonin; Thyroid nodes; Endocrinology; Public health; Healthy control |
| Core Tip |
A lady participating as healthy control in a study was found to suffer from a medullary thyroid cancer, a type of cancer in total surgical removal before the tumor has spread is the most important prognostic factor. The difficulty is the low diagnostic accuracy of ultrasound and procalcitonin-computed tomography scan, as well as the limitations of fine needle aspiration in a patient with several nodules. This case illustrates the consequences of volunteering as a “healthy control” in a clinical study. While early detection of the MCT was possible in our patient it paid off for her, but abnormal test results may also cause harm to patients if being false positive and leading to invasive procedures. |
| Publish Date |
2017-12-07 10:00 |
| Citation |
Giessen H, Nebiker CA, Bruehlmeier M, Spreitzer S, Mueller B, Schuetz P. Do you want to participate in a clinical study as a healthy control? - Risk or benefit? World J Clin Cases 2017; 5(12): 437-439 |
| URL |
http://www.wjgnet.com/2307-8960/full/v5/i12/437.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v5.i12.437 |
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