Publication Name	World Journal of Gastroenterology
Manuscript ID	3470
Country	China

Received	2013-05-01 14:30
Peer-Review Started	2013-05-02 16:50
First Decision by Editorial Office Director
Return for Revision	2013-05-28 14:59
Revised	2013-05-30 22:40
Publication Fee Transferred
Second Decision by Editor	2013-07-10 10:10
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-07-11 12:53
Articles in Press
Edit the Manuscript by Language Editor	2013-08-15 12:09
Typeset the Manuscript	2013-09-06 15:58
Publish the Manuscript Online	2013-09-21 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Autobiography
Article Title	Aberrant TGF-β1 signaling contributes to the development of primary biliary cirrhosis in murine model
Manuscript Source	Invited Manuscript
All Author List	Bin Liu, Xuan Zhang, Feng-Chun Zhang, Jin-Bao Zong, Wen Zhang and Yan Zhao
Funding Agency and Grant Number	Funding Agency Grant Number National Key Technology R and D Program in the 11th Five year Plan of China 2008BAI59B03 Emphasis Item Clinical Speciality, Ministry of Health of The People’s Republic of China 2005
Corresponding Author	Feng-Chun Zhang, MD, Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. zhangfccra@yahoo.com.cn
Key Words	Primary biliary cirrhosis; Transforming growth factor-β1; Regulatory T cell; Liver
Core Tip	Primary biliary cirrhosis (PBC) is an autoimmune liver disease. Recent studies suggest that transforming growth factor-β1 (TGF-β1) signaling pathway might play an important role in the pathogenesis of PBC. However, whether TGF-β1 signaling pathway is involved in the development of PBC is still unknown. The studies have provided new data of TGF-β1 signaling pathway involving the pathogenesis of PBC, which will pose significant impact on our understanding of the pathogeneses of PBC. TGF-β1 signaling pathway is a potential target for PBC treatment.
Publish Date	2013-09-21 09:08
Citation	Liu B, Zhang X, Zhang FC, Zong JB, Zhang W, Zhao Y. Aberrant TGF-β1 signaling contributes to the development of primary biliary cirrhosis in murine model. World J Gastroenterol 2013; 19(35): 5828-5836
URL	http://www.wjgnet.com/1007-9327/full/v19/i35/5828.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i35.5828

Full Article (PDF)	WJG-19-5828.pdf
Manuscript File	3470-Review.doc
Answering Reviewers	3470-Answering reviewers.pdf
Copyright License Agreement	3470-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate	3470-Language certificate.pdf
Peer-review Report	3470-Peer review(s).pdf
Scientific Editor Work List	3470-Scientific editor work list.doc