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8/19/2017 11:33:53 AM | Browse: 1128 | Download: 1786
Publication Name World Journal of Gastroenterology
Manuscript ID 34731
Country/Territory United States
Received
2017-05-19 04:59
Peer-Review Started
2017-05-19 14:00
To Make the First Decision
2017-06-22 00:38
Return for Revision
2017-06-23 10:35
Revised
2017-06-30 21:24
Second Decision
2017-07-11 05:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-07-12 07:04
Articles in Press
2017-07-12 07:04
Publication Fee Transferred
2017-07-26 03:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-08-11 12:07
Publish the Manuscript Online
2017-08-19 11:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Fluctuation of zonulin levels in blood vs stability of antibodies
Manuscript Source Unsolicited Manuscript
All Author List Aristo Vojdani, Elroy Vojdani and Datis Kharrazian
ORCID
Author(s) ORCID Number
Aristo Vojdani http://orcid.org/0000-0003-2925-9334
Elroy Vojdani http://orcid.org/0000-0001-8687-9762
Datis Kharrazian http://orcid.org/0000-0001-7985-476X
Funding Agency and Grant Number
Corresponding Author Aristo Vojdani, MSc, PhD, Immunosciences Lab., Inc., 822 S. Robertson Blvd., Ste. 312, Los Angeles, CA 90035, United States. drari@msn.com
Key Words Zonulin; Occludin; Tight junction protein; Intestinal barrier integrity; Celiac disease
Core Tip We studied possible variability in zonulin levels vs measuring antibodies against zonulin and other tight junction proteins in blood. We found that fluctuations in zonulin level from hour-to-hour and day-to-day were too great to recommend it for assessing intestinal permeability. Measurement of IgG and IgA antibodies against tight junction proteins in controls and in celiac disease patients proved to be very stable and reproducible, and we recommend this method for such an assessment in future studies.
Publish Date 2017-08-19 11:33
Citation Vojdani A, Vojdani E, Kharrazian D. Fluctuation of zonulin levels in blood vs stability of antibodies. World J Gastroenterol 2017; 23(31): 5669-5679
URL http://www.wjgnet.com/1007-9327/full/v23/i31/5669.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i31.5669
Full Article (PDF) WJG-23-5669.pdf
Full Article (Word) WJG-23-5669.doc
Manuscript File 34731-Review.docx
Answering Reviewers 34731-Answering reviewers.pdf
Audio Core Tip 34731-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34731-Conflict-of-interest statement.pdf
Copyright License Agreement 34731-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 34731-Institutional review board statement.pdf
Peer-review Report 34731-Peer-review(s).pdf
Scientific Misconduct Check 34731-Scientific misconduct check.pdf
Scientific Editor Work List 34731-Scientific editor work list.pdf