Publication Name	World Journal of Gastroenterology
Manuscript ID	34743
Country	Sweden

Received	2017-05-24 01:24
Peer-Review Started	2017-05-24 13:14
To Make the First Decision	2017-07-13 05:38
Return for Revision	2017-07-17 06:44
Revised	2017-07-31 14:29
Second Decision	2017-09-06 23:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-09-13 03:11
Articles in Press	2017-09-13 03:11
Publication Fee Transferred	2017-10-12 03:31
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-11-06 04:41
Publish the Manuscript Online	2017-11-12 06:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Physiology
Manuscript Type	Basic Study
Article Title	Induction of precocious intestinal maturation in T-cell deficient athymic neonatal rats
Manuscript Source	Unsolicited Manuscript
All Author List	Ester Arévalo Sureda, Catherine Gidlund, Björn Weström and Olena Prykhodko
ORCID	Author(s) ORCID Number Ester Arévalo Sureda http://orcid.org/0000-0002-3299-1510 Catherine Gidlund http://orcid.org/0000-0002-6622-5910 Björn Weström http://orcid.org/0000-0001-9296-2845 Olena Prykhodko http://orcid.org/0000-0002-5788-9176
Funding Agency and Grant Number	Funding Agency Grant Number Director Albert Påhlssons Foundation in Malmö, Sweden Royal Physiographic Society in Lund, Sweden
Corresponding Author	Ester Arévalo Sureda, PhD, Department of Biology, Lund University, Sölvegatan 35C, Lund 22362, Sweden. ester.arevalo_sureda@biol.lu.se
Key Words	Gut; Intestinal permeability; Passive immunity; Pancreas; Immunoglobulin G
Core Tip	The rat is born with an immature gut and is thus a suitable model to study gut development. Enteral provocation with phytohaemagglutinin or protease induces precocious gut maturation in conventional (euthymic) rats. It has been suggested that T-lymphocytes are required for gut digestive maturation. The current study showed that precocious gut maturation could be induced by enteral provocation in athymic nude rats similar to that which occurs in euthymic rats. The few intestinal mucosal CD3+-T-cells that were observed in the athymic nude rats appeared to be unaffected by enteral provocation. The intestinal absorptive capacity in nude pups was enhanced when nurtured by conventional (immunocompetent) foster dams.
Publish Date	2017-11-12 06:39
Citation	Arévalo Sureda E, Gidlund C, Weström B, Prykhodko O. Induction of precocious intestinal maturation in T-cell deficient athymic neonatal rats. World J Gastroenterol 2017; 23(42): 7531-7540
URL	http://www.wjgnet.com/1007-9327/full/v23/i42/7531.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i42.7531

Full Article (PDF)	WJG-23-7531.pdf
Full Article (Word)	WJG-23-7531.doc
Manuscript File	34743-Review.docx
Answering Reviewers	34743-Answering reviewers.pdf
Audio Core Tip	34743-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	34743-Conflict-of-interest statement.pdf
Copyright License Agreement	34743-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	34743-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	34743-Institutional animal care and use committee statement.pdf
Peer-review Report	34743-Peer-review(s).pdf
Scientific Misconduct Check	34743-Scientific misconduct check.pdf
Scientific Editor Work List	34743-Scientific editor work list.pdf