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12/5/2017 12:35:53 AM | Browse: 1122 | Download: 1358
Publication Name World Journal of Clinical Oncology
Manuscript ID 34757
Country/Territory United States
Received
2017-05-22 00:53
Peer-Review Started
2017-05-23 01:39
To Make the First Decision
2017-06-14 01:04
Return for Revision
2017-07-03 08:11
Revised
2017-08-23 03:39
Second Decision
2017-09-08 01:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-10-30 22:48
Articles in Press
2017-10-30 22:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-11-28 04:07
Publish the Manuscript Online
2017-12-05 00:35
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Epidemic of non-alcoholic fatty liver disease and hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Adnan Said and Aiman Ghufran
ORCID
Author(s) ORCID Number
Adnan Said http://orcid.org/0000-0001-9944-4071
Aiman Ghufran http://orcid.org/0000-0002-6352-1511
Funding Agency and Grant Number
Corresponding Author Adnan Said, Division of Gastroenterology and Hepatology, Department of Medicine, William S. Middleton VAMC, University of Wisconsin School of Medicine and Public Health, 4223 MFCB, 1685 Highland Avenue, Madison, WI 53705, United States. axs@medicine.wisc.edu
Key Words Non-alcoholic fatty liver disease; Hepatocellular carcinoma; Screening; Epidemiology; Pathophysiology; Diagnosis; Liver transplant; Resection; Locoregional therapy; Treatment
Core Tip Non-alcoholic fatty liver disease (NAFLD) related hepatocellular carcinoma (HCC) is rapidly in¬creasing worldwide. HCC in NAFLD is often detected at a more advanced stage than in hepatitis C virus (HCV). Challenges include earlier recognition of cirrhosis in NAFLD to allow earlier screening for liver cancer. NAFLD also has a higher proportion of HCC occurring in the absence of cirrhosis. Given the sheer number of patients with non-cirrhotic NAFLD, screening for HCC in this population is not practical. Instead prevention and treatment of non-alcoholic steatohepatitis to prevent cirrhosis should be an important strategy. When NAFLD-HCC is found at a curative stage, results with liver transplant, resection and loco-regional therapy are similar to that seen in HCV-HCC.
Publish Date 2017-12-05 00:35
Citation Said A, Ghufran A. Epidemic of non-alcoholic fatty liver disease and hepatocellular carcinoma. World J Clin Oncol 2017; 8(6): 429-436
URL http://www.wjgnet.com/2218-4333/full/v8/i6/429.htm
DOI http://dx.doi.org/10.5306/wjco.v8.i6.429
Full Article (PDF) WJCO-8-429.pdf
Full Article (Word) WJCO-8-429.doc
Manuscript File 34757-Review.doc
Answering Reviewers 34757-Answering reviewers.pdf
Audio Core Tip 34757-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34757-Conflict-of-interest statement.pdf
Copyright License Agreement 34757-Copyright assignment.pdf
Supplementary Material 34757-Supplementary-Material-revision.docx
Peer-review Report 34757-Peer-review(s).pdf
Scientific Editor Work List 34757-Scientific editor work list.pdf