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Articles Published Processes
12/5/2017 12:35:53 AM | Browse: 1262 | Download: 1660
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Received |
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2017-05-22 00:53 |
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Peer-Review Started |
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2017-05-23 01:39 |
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To Make the First Decision |
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2017-06-14 01:04 |
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Return for Revision |
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2017-07-03 08:11 |
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Revised |
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2017-08-23 03:39 |
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Second Decision |
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2017-09-08 01:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-10-30 22:48 |
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Articles in Press |
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2017-10-30 22:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-11-28 04:07 |
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Publish the Manuscript Online |
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2017-12-05 00:35 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Epidemic of non-alcoholic fatty liver disease and hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Adnan Said and Aiman Ghufran |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Adnan Said, Division of Gastroenterology and Hepatology, Department of Medicine, William S. Middleton VAMC, University of Wisconsin School of Medicine and Public Health, 4223 MFCB, 1685 Highland Avenue, Madison, WI 53705, United States. axs@medicine.wisc.edu |
| Key Words |
Non-alcoholic fatty liver disease; Hepatocellular carcinoma; Screening; Epidemiology; Pathophysiology; Diagnosis; Liver transplant; Resection; Locoregional therapy; Treatment |
| Core Tip |
Non-alcoholic fatty liver disease (NAFLD) related hepatocellular carcinoma (HCC) is rapidly in¬creasing worldwide. HCC in NAFLD is often detected at a more advanced stage than in hepatitis C virus (HCV). Challenges include earlier recognition of cirrhosis in NAFLD to allow earlier screening for liver cancer. NAFLD also has a higher proportion of HCC occurring in the absence of cirrhosis. Given the sheer number of patients with non-cirrhotic NAFLD, screening for HCC in this population is not practical. Instead prevention and treatment of non-alcoholic steatohepatitis to prevent cirrhosis should be an important strategy. When NAFLD-HCC is found at a curative stage, results with liver transplant, resection and loco-regional therapy are similar to that seen in HCV-HCC. |
| Publish Date |
2017-12-05 00:35 |
| Citation |
Said A, Ghufran A. Epidemic of non-alcoholic fatty liver disease and hepatocellular carcinoma. World J Clin Oncol 2017; 8(6): 429-436 |
| URL |
http://www.wjgnet.com/2218-4333/full/v8/i6/429.htm |
| DOI |
http://dx.doi.org/10.5306/wjco.v8.i6.429 |
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