Publication Name	World Journal of Nephrology
Manuscript ID	3482
Country

Received	2013-05-02 09:13
Peer-Review Started	2013-05-07 09:38
First Decision by Editorial Office Director
Return for Revision	2013-05-28 17:37
Revised	2013-06-04 19:52
Publication Fee Transferred
Second Decision by Editor	2013-09-03 14:20
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-09-04 07:27
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-23 19:04
Publish the Manuscript Online	2013-11-04 12:41

ISSN	2220-6124 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Minireviews
Article Title	Vascular response to vasodilator treatment in microalbuminuric diabetic kidney disease
Manuscript Source
All Author List	Narisa Futrakul and Prasit Futrakul
Funding Agency and Grant Number
Corresponding Author	Narisa Futrakul, MD, PhD, Professor, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand. fmednft@yahoo.com
Key Words	Microalbuminuria; Diabetic kidney disease; Renal hemodynamics; Fractional excretion of magnesium; Renal function
Core Tip	This manuscript demonstrates the therapeutic resistance to vasodilator treatment in restoring the renal functions in microalbuminuric diabetic nephropathy. It is supported by the intrarenal hemodynamic study which reveals a decline in renal plasma flow, peritubular capillary flow and glomerular filtration rate following vasodilator treatment. The above finding concerns with the recent study on vascular homeostasis which reveals a defective angiogenesis associated with an impaired nitric oxide production, which explains the therapeutic resistance to vasodilator and clinical failure in restoring renal perfusion in late stage diabetic nephropathy.
Publish Date	2013-11-04 12:41
Citation	Futrakul N, Futrakul P. Vascular response to vasodilator treatment in microalbuminuric diabetic kidney disease. World J Nephrol 2013; 2(4): 125-128
URL	http://www.wjgnet.com/2220-6124/full/v2/i4/125.htm
DOI	http://dx.doi.org/10.5527/wjn.v2.i4.125

Full Article (PDF)	WJN-2-125.pdf
Manuscript File	3482-Review.doc
Answering Reviewers	3482-Answering reviewers.pdf
Copyright License Agreement	3482-Copyright assignment.pdf
Peer-review Report	3482-Peer review(s).pdf
Scientific Editor Work List	3482-Scientific editor work list.doc