Publication Name	World Journal of Diabetes
Manuscript ID	3484
Country	Denmark

Received	2013-05-02 09:23
Peer-Review Started	2013-05-07 11:29
To Make the First Decision	2013-06-09 10:12
Return for Revision	2013-07-10 17:01
Revised	2013-07-19 19:36
Second Decision	2013-10-17 13:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-10-18 06:57
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-06 09:25
Publish the Manuscript Online	2013-12-20 16:49

ISSN	1948-9358 (online)
Open Access
Copyright
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Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Changes of phasic and tonic smooth muscle function of jejunum in type 2 diabetic Goto-Kakizaki rats
Manuscript Source	Invited Manuscript
All Author List	Jing-Bo Zhao, Peng-Min Chen and Hans Gregersen
Funding Agency and Grant Number	Funding Agency Grant Number Karen Elise Jensens Foundation
Corresponding Author	Jing-Bo Zhao, Associate Professor, Mech-Sense, Department of Gastroenterology and Surgery, Aalborg University Hospital, Sdr. Skovvej 15, DK9000 Aalborg, Denmark. jz@rn.dk
Key Words	Intestine; Diabetes; Muscle function; Stress-strain curves; Carbachol; Rat
Core Tip	Length-tension diagrams of smooth muscle strips were obtained in intact segment of intestine in vitro in the present study. We demonstrated that it is a valid tool to evaluate smooth muscle function in intact intestine. Diabetes decreased the force (stress) generated by the smooth muscle normalized to the muscle layer thickness. Since the stress decreased and the muscle layer thickness increased in diabetic rats, it indicates that the intestine, at least in part, remodels in a stress-dependent way. Furthermore, the smooth muscle in Goto-Kakizaki diabetic intestine preserved its response to carbachol stimulation.
Publish Date	2013-12-20 16:49
Citation	Zhao JB, Chen PM, Gregersen H. Changes of phasic and tonic smooth muscle function of jejunum in type 2 diabetic Goto-Kakizaki rats. World J Diabetes 2013; 4(6): 339-348 Available from: URL: http://www.wjgnet.com/1948-9358/full/v4/i6/339.htm DOI: http://dx.doi.org/10.4239/wjd.v4.i6.339
URL	http://www.wjgnet.com/1948-9358/full/v4/i6/339.htm
DOI	http://dx.doi.org/10.4239/wjd.v4.i6.339

Full Article (PDF)	WJD-4-339.pdf
Full Article (Word)	WJD-4-339.doc
Manuscript File	3484-Review.doc
Answering Reviewers	3484-Answering reviewers.pdf
Copyright License Agreement	3484-Copyright assignment.pdf
Peer-review Report	3484-Peer reviewer(s).pdf
Scientific Editor Work List	3484-Scientific editor work list.doc