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Articles Published Processes
11/1/2017 9:02:15 AM | Browse: 1189 | Download: 1872
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Received |
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2017-06-08 01:17 |
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Peer-Review Started |
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2017-06-08 07:33 |
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To Make the First Decision |
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2017-08-08 01:09 |
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Return for Revision |
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2017-08-08 08:03 |
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Revised |
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2017-08-21 08:18 |
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Second Decision |
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2017-09-08 09:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-09-15 00:35 |
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Articles in Press |
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2017-09-15 00:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-10-31 03:56 |
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Publish the Manuscript Online |
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2017-11-01 09:02 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Association of miR-146 rs2910164, miR-196a rs11614913, miR-221 rs113054794 and miR-224 rs188519172 polymorphisms with anti-TNF treatment response in a Greek population with Crohn’s disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ioannis Papaconstantinou, Christina Kapizioni, Evangelia Legaki, Elena Xourgia, George Karamanolis, Antonios Gklavas and Maria Gazouli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maria Gazouli, Associate Professor, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Michalakopoulou 176, Athens 11527, Greece. mgazouli@med.uoa.gr |
| Key Words |
MicroRNA; Crohn’s disease; Polymorphisms; Anti-TNF; Biomarkers |
| Core Tip |
Anti-TNF agents are the cornerstone of inflammatory bowel disease (IBD) treatment strategy so far though not effective in one third of patients in the first months of administration. Biomarkers for prediction of each patient’s treatment response are vigorously sought in the era of personalized medicine. MicroRNAs have been studied as possible predictors of response to therapy in cancer and autoimmune diseases including IBD. MiRNA polymorphisms though have never been studied in IBD as markers of anti-TNF response. Our results suggest that for rs2910164, rs11614913, rs113054794, and rs188519172 no association to anti-TNF agents’ response in patients with Crohn’s disease can be established. |
| Publish Date |
2017-11-01 09:02 |
| Citation |
Papaconstantinou I, Kapizioni C, Legaki E, Xourgia E, Kara¬manolis G, Gklavas A, Gazouli M. Association of miR-146 rs2910164, miR-196a rs11614913, miR-221 rs113054794 and miR-224 rs188519172 polymorphisms with anti-TNF treatment response in a Greek population with Crohn’s disease. World J Gastrointest Pharmacol Ther 2017; 8(4): 193-200 |
| URL |
http://www.wjgnet.com/2150-5349/full/v8/i4/193.htm |
| DOI |
http://dx.doi.org/10.4292/wjgpt.v8.i4.193 |
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