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Articles Published Processes
12/7/2017 10:00:55 AM | Browse: 943 | Download: 1330
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Received |
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2017-06-13 02:34 |
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Peer-Review Started |
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2017-06-15 00:33 |
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To Make the First Decision |
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2017-08-04 01:59 |
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Return for Revision |
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2017-08-07 05:30 |
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Revised |
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2017-08-11 15:18 |
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Second Decision |
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2017-08-28 09:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-09-04 18:19 |
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Articles in Press |
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2017-09-04 18:19 |
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Publication Fee Transferred |
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2017-09-25 03:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-11-28 04:10 |
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Publish the Manuscript Online |
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2017-12-07 10:00 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Case Report |
| Article Title |
Topiramate induced peripheral neuropathy: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Sherifa Ahmed Hamed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sherifa Ahmed Hamed, MD, Doctor, Doctor, Professor, Department of Neurology and Psychiatry, Assiut University Hospital, Floor # 7, Room # 4, Assiut 71516, Egypt. sherifa.omran@med.au.edu.eg |
| Key Words |
Topiramate; Peripheral neuropathy; Sodium channel blockade; Antiepileptic drugs |
| Core Tip |
Peripheral neuropathy is a rare adverse effect of short- or long-term use of antiepileptic drugs (phenytoin, phenobarbital, carbamazepine, valproate, gabapentin, levetiracetam and lacosamide). This is the first case report of topiramate induced peripheral neuropathy (TIPN). Manifestations of TIPN are distal paresthesia, areflexia, sensory deficits and reduced amplitudes and nerve conduction velocities of motor and sensory peripheral nerves of the lower extremities indicating demyelinating and axonal neuropathies. The risk is greater with long-term therapy. The mechanisms of TIPN may involve impairment of nerve function through blocking of sodium voltage channels, enhancement of gamma amino butyric acid inhibitory neurotransmission or others. |
| Publish Date |
2017-12-07 10:00 |
| Citation |
Hamed SA. Topiramate induced peripheral neuropathy: A case report and review of literature. World J Clin Cases 2017; 5(12): 446-452 |
| URL |
http://www.wjgnet.com/2307-8960/full/v5/i12/446.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v5.i12.446 |
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