Publication Name	World Journal of Gastroenterology
Manuscript ID	350
Country	Italy

Received	2012-08-31 20:30
Peer-Review Started	2012-08-31 21:55
To Make the First Decision	2012-09-19 14:29
Return for Revision	2013-01-08 21:26
Revised	2013-01-19 19:10
Second Decision	2013-03-15 18:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-03-15 23:01
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-05-08 15:56
Publish the Manuscript Online	2013-05-14 16:05

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Sustained virological response: A milestone in the treatment of chronic hepatitis C
Manuscript Source	Invited Manuscript
All Author List	Filomena Morisco, Rocco Granata, Tommaso Stroffolini, Maria Guarino, Laura Donnarumma, Laura Gaeta, Ilaria Loperto, Ivan Gentile, Francesco Auriemma and Nicola Caporaso
Funding Agency and Grant Number
Corresponding Author	Filomena Morisco, MD, Chair of Gastroenterology, Dipartimento di Medicina Clinica e Chirurgia, Gastroenterology Unit, University of Naples “Federico Ⅱ”, Via S Pansini, 5, 80131 Naples, Italy. filomena.morisco@unina.it
Key Words	Antiviral therapy; Cirrhosis; Hepatitis C virus; Sustained virological response; Fibrosis
Core Tip	This study represents one of the longest follow-up studies on the natural history of successfully treated chronically hepatitis C virus (HCV) infected individuals. The outcome of the study was very positive, as it revealed an extremely high survival rate, an extremely low rate of liver complications, and a significant reduction in liver fibrosis in patients who have achieved sustained virological response (SVR). All of the patients without cirrhosis before starting the treatment showed no signs of evolution or decompensation over the years of observation, proving that SVR positively changes the natural history in individuals with HCV-infection.
Publish Date	2013-05-14 16:05
Citation	Morisco F, Granata R, Stroffolini T, Guarino M, Donnarumma L, Gaeta L, Loperto I, Gentile I, Auriemma F, Caporaso N. Sustained virological response: A milestone in the treatment of chronic hepatitis C. World J Gastroenterol 2013; 19(18): 2793-2798
URL	http://www.wjgnet.com/1007-9327/full/v19/i18/2793.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i18.2793

Full Article (PDF)	WJG-19-2793.pdf
Manuscript File	350-Review.doc
Answering Reviewers	350-Answering reviewers.doc
Copyright License Agreement	350-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	350-Language certificate.pdf
Peer-review Report	350-Peer review(s).docx
Scientific Editor Work List	350-Scientific editor work list.doc