Publication Name	World Journal of Gastroenterology
Manuscript ID	3515
Country	Brazil

Received	2013-05-03 11:39
Peer-Review Started	2013-05-03 21:39
To Make the First Decision	2013-05-23 17:16
Return for Revision	2013-05-24 11:43
Revised	2013-06-15 02:55
Second Decision	2013-07-05 11:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-07-05 13:10
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-05 09:42
Publish the Manuscript Online	2014-03-12 14:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Meta-Analysis
Article Title	Serrated pathway in colorectal carcinogenesis
Manuscript Source	Invited Manuscript
All Author List	Letícia Yamane, Cristovam Scapulatempo-Neto, Rui Manuel Reis and Denise Peixoto Guimarães
Funding Agency and Grant Number
Corresponding Author	Denise Peixoto Guimarães, MD, PhD, Department of Endoscopy, Barretos Cancer Hospital, Rua Antenor Duarte Vilella, 1331, Barretos, 14780-000 São Paulo, Brazil. guimaraes.dp@gmail.com
Key Words	Serrated pathway; Colorectal carcinogenesis; Mutation; Microsatellite instability; CpG island methylator phenotype
Core Tip	This paper reviews the pathologic and molecular features of serrated polyps and the serrated pathway to colorectal cancer and its clinical impact. The serrated pathway has recently emerged as the second pathway leading to colorectal cancer, and the genetic alterations occurring in this pathway are not still clarified. It’s imperative to understand the molecular profile of colorectal lesions with higher malignancy potential to implement a surveillance and screening approach in order to prevent colorectal cancer development.
Publish Date	2014-03-12 14:46
Citation	Yamane L, Scapulatempo-Neto C, Reis RM, Guimar?es DP. Serrated pathway in colorectal carcinogenesis. World J Gastroenterol 2014; 20(10): 2634-2640
URL	http://www.wjgnet.com/1007-9327/full/v20/i10/2634.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i10.2634

Full Article (PDF)	WJG-20-2634.pdf
Full Article (Word)	WJG-20-2634.doc
Manuscript File	3515-Review.doc
Answering Reviewers	3515-Answering reviewers.pdf
Copyright License Agreement	3515-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3515-Language certificate.pdf
Peer-review Report	3515-Peer reviews.pdf
Scientific Editor Work List	3515-Scientific editor work list.doc