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Articles Published Processes
10/21/2017 7:10:38 AM | Browse: 1315 | Download: 1838
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Received |
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2017-07-24 03:18 |
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Peer-Review Started |
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2017-07-24 12:06 |
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To Make the First Decision |
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2017-08-15 03:48 |
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Return for Revision |
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2017-08-21 00:39 |
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Revised |
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2017-08-27 13:03 |
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Second Decision |
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2017-09-06 23:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-09-13 03:00 |
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Articles in Press |
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2017-09-13 03:00 |
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Publication Fee Transferred |
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2017-09-21 03:05 |
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Edit the Manuscript by Language Editor |
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2017-09-26 18:21 |
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Typeset the Manuscript |
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2017-10-12 03:12 |
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Publish the Manuscript Online |
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2017-10-21 07:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Integrative & Complementary Medicine |
| Manuscript Type |
Basic Study |
| Article Title |
Optimal timing for the oral administration of Da-Cheng-Qi decoction based on the pharmacokinetic and pharmacodynamic targeting of the pancreas in rats with acute pancreatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Mei Zhang, Lin Zhu, Xian-Lin Zhao, Huan Chen, Hong-Xin Kang, Jian-Lei Zhao, Mei-Hua Wan, Juan Li, Lv Zhu and Wen-Fu Tang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
81374042 |
| the National Natural Science Foundation of China |
81370091 |
| the National Natural Science Foundation of China |
81603480 |
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| Corresponding Author |
Wen-Fu Tang, PhD, Professor, Department of Integrative Medicine, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, Sichuan Province, China. tangwf@scu.edu.cn |
| Key Words |
Da-Cheng-Qi decoction; Acute pancreatitis; Pharmacokinetics; Oral dosing time; Pharmacodynamics |
| Core Tip |
Our study group had raised the hypothesis of tissue pharmacology of an herbal recipe, which assumed the effect of an herb formula is related to its target tissue distribution or concentration of effective components in target tissues. This study was then designed to screen the optimal oral dosing time of Da-Cheng-Qi decoction (DCQD) in rats with acute pancreatitis based on the pharmacokinetics of the main absorbed components and the pharmacodynamics of DCQD targeting of the pancreas. |
| Publish Date |
2017-10-21 07:10 |
| Citation |
Zhang YM, Zhu L, Zhao XL, Chen H, Kang HX, Zhao JL, Wan MH, Li J, Zhu L, Tang WF. Optimal timing for the oral administration of Da-Cheng-Qi decoction based on the pharmacokinetic and pharmacodynamic targeting of the pancreas in rats with acute pancreatitis. World J Gastroenterol 2017; 23(39): 7098-7109 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i39/7098.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i39.7098 |
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