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Articles Published Processes
11/17/2017 9:05:21 AM | Browse: 1324 | Download: 1863
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Received |
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2017-07-17 00:21 |
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Peer-Review Started |
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2017-07-19 08:07 |
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To Make the First Decision |
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2017-08-07 00:42 |
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Return for Revision |
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2017-08-07 08:06 |
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Revised |
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2017-08-17 17:57 |
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Second Decision |
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2017-08-28 09:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-09-05 04:08 |
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Articles in Press |
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2017-09-05 04:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-11-14 03:32 |
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Publish the Manuscript Online |
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2017-11-17 09:05 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Clinical Trials Study |
Article Title |
Value of histomorphometric tumour thickness and smoothelin for conventional m-classification in early oesophageal adenocarcinoma
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Manuscript Source |
Invited Manuscript |
All Author List |
Katharina Endhardt, Bruno Märkl, Andreas Probst, Tina Schaller and Daniela Aust |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Bruno Märkl, MD, Institute of Pathology, Klinikum Augsburg, Stenglinstr 2, Augsburg 86156, Germany. bruno.maerkl@klinikum-augsburg.de |
Key Words |
Endoscopic submucosal dissection; Muscularis mucosae; Adenocarcinoma; Barrett’s carcinoma; Smoothelin |
Core Tip |
The aim of this study was to determine whether histomorphometric measurement of tumor thickness and immunohistochemical staining for smoothelin facilitate the exact pT substaging in early oesophageal adenocarcinoma. Our data showed that there is clear cut-off of 1000 µm to distinguish advanced early lesions (M4/sm1) from such lesions that do not reach the deep muscularis mucosae or the submucosa. Moreover, smoothelin staining is of help to distinguish the superficial from the deep muscularis mucosa by different staining intensities. Therfore, both methods could be shown to be of help for the often challenging task to T-classify early oesophageal adenocarcinomas. |
Publish Date |
2017-11-17 09:05 |
Citation |
Endhardt K, Märkl B, Probst A, Schaller T, Aust D. Value of histomorphometric tumour thickness and smoothelin for conventional m-classification in early oesophageal adenocarcinoma. World J Gastrointest Oncol 2017; In press |
URL |
http://www.wjgnet.com/1948-5204/full/v9/i11/444.htm |
DOI |
http://dx.doi.org/10.4251/wjgo.v9.i11.444 |
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