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Articles Published Processes
11/20/2017 4:03:35 AM | Browse: 1301 | Download: 1839
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Received |
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2017-07-24 04:08 |
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Peer-Review Started |
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2017-07-24 12:30 |
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To Make the First Decision |
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2017-08-30 03:26 |
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Return for Revision |
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2017-09-04 01:58 |
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Revised |
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2017-09-13 11:53 |
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Second Decision |
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2017-09-28 07:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-09-28 18:18 |
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Articles in Press |
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2017-09-28 18:18 |
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Publication Fee Transferred |
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2017-10-10 14:23 |
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Edit the Manuscript by Language Editor |
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2017-11-06 21:38 |
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Typeset the Manuscript |
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2017-11-13 01:40 |
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Publish the Manuscript Online |
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2017-11-20 04:03 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Minireviews |
| Article Title |
Pathological process of liver sinusoidal endothelial cells in liver diseases
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yao Ni, Juan-Mei Li, Ming-Kun Liu, Ting-Ting Zhang, Dong-Ping Wang, Wen-Hui Zhou, Ling-Zi Hu and Wen-Liang lv |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the financial supports from the Young Elite Scientists Sponsorship Program by CAST |
2016QNRC001 |
| Beijing Natural Science Foundation |
No.7172187 |
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| Corresponding Author |
Wen-Liang lv, PhD, Professor, Department of Infection, Guang' anmen Hospital, China Academy of Chinese medical Sciences, No. 5, Bei Xian-ge Road, Beijing 100053, China. lvwenliang@sohu.com |
| Key Words |
Sinusoidal endothelial cells; Hepatitis; Fibrosis; Cirrhosis; Liver disease |
| Core Tip |
Liver sinusoidal endothelial cells (LSECs) comprise the highest proportion of nonparenchymal cells in the liver. Their fenestrae and basement membrane structure, and high endocytic clearance ability play an indispensable role in the physiology and pathology of the liver. LSECs mainly participate in the regulation of liver pathology, such as hepatitis, liver fibrosis, cirrhosis and liver regeneration, by exerting anti-inflammatory activity, endocytosis, secretion, synthesis of angiogenesis signaling molecules and maintaining the hepatic stellate cell phenotype. It is important to elucidate the mechanism of action of LSECs, which will provide important information for future targeted therapy and clinical diagnosis. |
| Publish Date |
2017-11-20 04:03 |
| Citation |
Ni Y, Li JM, Liu MK, Zhang TT, Wang DP, Zhou WH, Hu LZ, Lv WL. Pathological process of liver sinusoidal endothelial cells in liver diseases. World J Gastroenterol 2017; 23(43): 7666-7677 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i43/7666.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i43.7666 |
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