Publication Name	World Journal of Gastroenterology
Manuscript ID	35478
Country	China

Received	2017-07-24 04:08
Peer-Review Started	2017-07-24 12:30
To Make the First Decision	2017-08-30 03:26
Return for Revision	2017-09-04 01:58
Revised	2017-09-13 11:53
Second Decision	2017-09-28 07:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-09-28 18:18
Articles in Press	2017-09-28 18:18
Publication Fee Transferred	2017-10-10 14:23
Edit the Manuscript by Language Editor	2017-11-06 21:38
Typeset the Manuscript	2017-11-13 01:40
Publish the Manuscript Online	2017-11-20 04:03

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Minireviews
Article Title	Pathological process of liver sinusoidal endothelial cells in liver diseases
Manuscript Source	Unsolicited Manuscript
All Author List	Yao Ni, Juan-Mei Li, Ming-Kun Liu, Ting-Ting Zhang, Dong-Ping Wang, Wen-Hui Zhou, Ling-Zi Hu and Wen-Liang lv
ORCID	Author(s) ORCID Number Yao Ni http://orcid.org/0000000242032284 Juan-Mei Li http://orcid.org/0000000168199720 Ming-Kun Liu http://orcid.org/0000000347877654 Ting-Ting Zhang http://orcid.org/0000000242284721 Dong-Ping Wang http://orcid.org/0000000307816013 Wen-Hui Zhou http://orcid.org/0000000341598320 Ling-Zi Hu http://orcid.org/0000000277001154 Wen-Liang lv http://orcid.org/0000000268664394
Funding Agency and Grant Number	Funding Agency Grant Number the financial supports from the Young Elite Scientists Sponsorship Program by CAST 2016QNRC001 Beijing Natural Science Foundation No.7172187
Corresponding Author	Wen-Liang lv, PhD, Professor, Department of Infection, Guang' anmen Hospital, China Academy of Chinese medical Sciences, No. 5, Bei Xian-ge Road, Beijing 100053, China. lvwenliang@sohu.com
Key Words	Sinusoidal endothelial cells; Hepatitis; Fibrosis; Cirrhosis; Liver disease
Core Tip	Liver sinusoidal endothelial cells (LSECs) comprise the highest proportion of nonparenchymal cells in the liver. Their fenestrae and basement memb­rane structure, and high endocytic clearance ability play an indispensable role in the physiology and pathology of the liver. LSECs mainly participate in the regulation of liver pathology, such as hepatitis, liver fibrosis, cirrhosis and liver regeneration, by exerting anti-inflammatory activity, endocytosis, secretion, synthesis of angiogenesis signaling molecules and maintaining the hepatic stellate cell phenotype. It is important to elucidate the mechanism of action of LSECs, which will provide important information for future targeted therapy and clinical diagnosis.
Publish Date	2017-11-20 04:03
Citation	Ni Y, Li JM, Liu MK, Zhang TT, Wang DP, Zhou WH, Hu LZ, Lv WL. Pathological process of liver sinusoidal endothelial cells in liver diseases. World J Gastroenterol 2017; 23(43): 7666-7677
URL	http://www.wjgnet.com/1007-9327/full/v23/i43/7666.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i43.7666

Full Article (PDF)	WJG-23-7666.pdf
Full Article (Word)	WJG-23-7666.doc
Manuscript File	35478-Review.doc
Answering Reviewers	35478-Answering reviewers.pdf
Audio Core Tip	35478-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	35478-Conflict-of-interest statement.pdf
Copyright License Agreement	35478-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	35478-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s)-revision.pdf
Non-Native Speakers of English Editing Certificate	35478-Non-Native-Speakers-of-English-revision.pdf
Peer-review Report	35478-Peer-review(s).pdf
Scientific Misconduct Check	35478-Scientific misconduct check.pdf
Scientific Editor Work List	35478-Scientific editor work list.pdf