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Articles Published Processes
11/27/2017 2:36:57 AM | Browse: 1265 | Download: 2590
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Received |
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2017-07-28 01:05 |
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Peer-Review Started |
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2017-07-28 02:05 |
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First Decision by Editorial Office Director |
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2017-08-30 00:41 |
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Return for Revision |
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2017-09-04 07:20 |
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Revised |
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2017-09-25 13:26 |
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Publication Fee Transferred |
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2017-11-02 04:17 |
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Second Decision by Editor |
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2017-09-28 10:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2017-09-28 18:16 |
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Articles in Press |
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2017-09-28 18:16 |
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Edit the Manuscript by Language Editor |
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2017-11-11 21:23 |
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Typeset the Manuscript |
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2017-11-17 02:14 |
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Publish the Manuscript Online |
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2017-11-27 02:36 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ka-Shing Cheung, Wai-Kay Seto, James Fung, Lung-Yi Mak, Ching-Lung Lai and Man-Fung Yuen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Man-Fung Yuen, Professor, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong , China. mfyuen@hkucc.hku.hk |
| Key Words |
Aspartate aminotransferase; Platelet ratio index; Hepatocellular carcinoma; Primary biliary cholangitis; Ursodeoxycholic acid; Cirrhosis |
| Core Tip |
Currently, no reliable predictive models exist for hepatocellular carcinoma (HCC) in primary biliary cholangitis (PBC). Our study showed that a higher aspartate aminotransferase to platelet ratio index (APRI) at 1 year after treatment (APRI-r1) was associated with a higher HCC risk. The performance of APRI-r1 in predicting HCC was satisfactory (area under receiver operating curve: 0.77). Combination of APRI-r1 with treatment response further stratified HCC risk. Owing to its simplicity, non-invasiveness and cost-effectiveness, APRI can be used as a marker to streamline the HCC surveillance protocol in PBC patients. |
| Publish Date |
2017-11-27 02:36 |
| Citation |
Cheung KS, Seto WK, Fung J, Mak LY, Lai CL, Yuen mf. Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis. World J Gastroenterol 2017; 23(44): 7863-7874 |
| URL |
http://www.wjgnet. com/1007-9327/full/v23/i44/7863.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i44.7863 |
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