Publication Name	World Journal of Gastroenterology
Manuscript ID	3558
Country	Japan

Received	2013-05-06 17:52
Peer-Review Started	2013-05-07 10:05
To Make the First Decision	2013-06-09 10:10
Return for Revision	2013-06-19 19:59
Revised	2013-07-19 18:02
Second Decision	2013-08-08 19:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-08-09 01:09
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-09-11 15:08
Publish the Manuscript Online	2013-09-26 18:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Liver metastasis is the only independent prognostic factor in AFP-producing gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Shoji Hirajima, Shuhei Komatsu, Daisuke Ichikawa, Takeshi Kubota, Kazuma Okamoto, Atsushi Shiozaki, Hitoshi Fujiwara, Hirotaka Konishi, Hisashi Ikoma and Eigo Otsuji
Funding Agency and Grant Number
Corresponding Author	Shuhei Komatsu, MD, Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto 602-8566, Japan. skomatsu@koto.kpu-m.ac.jp
Key Words	α-fetoprotein; Gastric cancer; Liver metastasis; Poor prognosis; Immunostaining
Core Tip	In the present study, we re-evaluated the clinicopathological characteristics and clinical outcomes of consecutive patients with 飦?fetoprotein (AFP)-producing gastric cancer (GC). The results obtained clearly demonstrated that clinical behaviors were different between patients with and without AFP-producing GC. However, the prognosis according to the presence or absence of liver metastasis was similar between patients with and without AFP-producing GC. Our results show that liver metastasis should be specifically targeted in an effort to improve the prognosis of AFP-producing GC.
Publish Date	2013-09-26 18:39
Citation	Hirajima S, Komatsu S, Ichikawa D, Kubota T, Okamoto K, Shiozaki A, Fujiwara H, Konishi H, Ikoma H, Otsuji E. Liver metastasis is the only independent prognostic factor in AFP-producing gastric cancer. World J Gastroenterol 2013; 19(36): 6055-6061
URL	http://www.wjgnet.com/1007-9327/full/v19/i36/6055.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i36.6055

Full Article (PDF)	WJG-19-6055.pdf
Manuscript File	3558-Review.doc
Answering Reviewers	3558-Answering reviewers.pdf
Copyright License Agreement	3558-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3558-Language certificate.pdf
Peer-review Report	3558-Peer reviewer(s).pdf
Scientific Editor Work List	3558-Scientific editor work list.doc