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Articles Published Processes
8/27/2014 5:15:00 PM | Browse: 952 | Download: 919
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Received |
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2013-05-07 07:43 |
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Peer-Review Started |
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2013-05-07 10:02 |
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To Make the First Decision |
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2013-06-09 10:10 |
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Return for Revision |
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2013-06-19 20:41 |
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Revised |
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2013-07-12 01:50 |
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Second Decision |
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2013-12-03 20:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2013-12-04 06:26 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-04-03 04:51 |
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Typeset the Manuscript |
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2014-04-29 11:07 |
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Publish the Manuscript Online |
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2014-05-18 12:31 |
Category |
Pathology |
Manuscript Type |
Autobiography |
Article Title |
Frequency of HER2/neu overexpression in adenocarcinoma of the gastrointestinal system
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Manuscript Source |
Invited Manuscript |
All Author List |
Sadaf Farzand, Tahir Siddique, Kanwal Saba and Mulazim Hussain Bukhari |
Funding Agency and Grant Number |
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Corresponding Author |
Mulazim Hussain Bukhari, Professor, Department of Pathobiology, King Edward Medical University, Nila Gumbad, Anarkali, Lahore 54000, Pakistan. mulazim.hussain@gmail.com |
Key Words |
HER2/neu; Immunohistochemistry; Adenocarcinoma; Gastrointestinal system |
Core Tip |
The role of HER2/neu was seen in 50 cases of gastrointestinal adenocarcinoma by immunohistochemistry. Overall, HER2/neu protein overexpression was found in 33 (66%) patients (P = 0.000), with 23 (69.6%) being colorectal carcinoma while the remaining 10 (30%) were gastric carcinoma. There was highly significant association between tumor grades and HER2/neu protein overexpression. HER2/neu protein was overexpressed in those adenocarcinomas showing a significant association between grade of tumor and HER2/neu protein overexpression. This discovery may improve treatment options for cases of gastric and colorectal carcinomas.
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Publish Date |
2014-05-18 12:31 |
Citation |
Farzand S, Siddique T, Saba K, Bukhari MH. Frequency of HER2/neu overexpression in adenocarcinoma of gastrointestinal system. World J Gastroenterol 2014; 20(19): 5889-5896 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i19/5889.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i19.5889 |
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