| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Stricturing Crohn’s disease-like colitis in a patient treated with belatacept
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Anne Bozon, Guillaume Jeantet, Benjamin Rivière, Natalie Funakoshi, Gaspard Dufour, Roman Combes, Jean-Christophe Valats, Sylvie Delmas, Jean emmanuel Serre, Michael Bismuth, Jeanne Ramos, Moglie Le Quintrec, Pierre Blanc and Guillaume Pineton de Chambrun |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Guillaume Pineton de Chambrun, MD, PhD, Assistant Professor, Department of Gastroenterology, Saint-Eloi Hospital, Montpellier University Hospital, 80 avenue Augustin Fliche, Montpellier 34000, France. gpinetondechambrun@yahoo.fr |
| Key Words |
Inflammatory bowel disease; Crohn’s disease; Colitis; Belatacept; HHV-6 |
| Core Tip |
Belatacept is a cytotoxic T-lymphocyte-associated antigen 4 Ig fusion protein used for kidney transplant rejection prophylaxis. We report the appearance of a severe stricturing Crohn’s disease-like colitis in a patient who was treated with belatacept. After belatacept withdrawal, complete mucosal healing was observed with the persistence of a non-ulcerated left-sided colonic stricture which did not allow passage of the colonoscope. So, in patients treated with belatacept who develop digestive symptoms such as diarrhea or intestinal bleeding, we recommend performing early colonoscopy and considering belatacept withdrawal in case of suggestive endoscopic and histologic findings in order to avoid colonic sequela. |
| Publish Date |
2017-12-27 11:08 |
| Citation |
Bozon A, Jeantet G, Rivière B, Funakoshi N, Dufour G, Combes R, Valats JC, Delmas S, Serre JE, Bismuth M, Ramos J, Le Quintrec M, Blanc P, Pineton de Chambrun G. Stricturing Crohn’s disease-like colitis in a patient treated with belatacept. World J Gastroenterol 2017; 23(48): 8660-8665 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i48/8660.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i48.8660 |
