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1/31/2018 1:17:45 AM | Browse: 807 | Download: 1061
Publication Name World Journal of Gastroenterology
Manuscript ID 35979
Country China
Received
2017-08-26 22:08
Peer-Review Started
2017-08-27 02:30
To Make the First Decision
2017-09-13 00:54
Return for Revision
2017-09-13 02:44
Revised
2017-09-26 16:20
Second Decision
2017-11-21 11:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-21 18:53
Articles in Press
2017-11-21 18:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-12-04 01:26
Typeset the Manuscript
2018-01-15 08:09
Publish the Manuscript Online
2018-01-31 01:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Promotion of Sema4D expression by tumor-associated macrophages: Significance in gastric carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Han Li, Jin-Shen Wang, Lin-Jun Mu, Ke-Shu Shan, Le-Ping Li and Yan-Bing Zhou
ORCID
Author(s) ORCID Number
Han Li http://orcid.org/0000-0001-6804-3398
Jin-Shen Wang http://orcid.org/0000-0002-1709-5718
Lin-Jun Mu http://orcid.org/0000-0003-1214-5517
Ke-Shu Shan http://orcid.org/0000-0001-5907-2189
Le-Ping Li http://orcid.org/0000-0002-9421-6122
Yan-Bing Zhou http://orcid.org/0000-0001-7186-8833
Funding Agency and Grant Number
Corresponding Author Yan-Bing Zhou, PhD, Chief Doctor, Department of Gastrointestinal Surgery, Affilated Hospital of Qingdao University, Qingdao 266071, Shandong, China. didi8114@163.com
Key Words Gastric carcinoma; CD68; Semaphorin 4D; Tumor-associated macrophages
Core Tip This study explored the role and clinical significance of semaphorin 4D (Sema4D) expression promoted by tumor-associated macrophages (TAMs) in gastric carcinoma cells. By using immunohistochemical streptavidin-peroxidase method on tissue species and gastric carcinoma cells in non-contact co-culture with human M2 macrophages in vitro, we found that Sema4D protein expression was significantly higher in gastric carcinoma tissues than in adjacent normal tissues, and TAMs promoted the invasion and metastasis of gastric carcinoma cells possibly through upregulated Sema4D protein expression.
Publish Date 2018-01-31 01:17
Citation Li H, Wang JS, Mu LJ, Shan KS, Li LP, Zhou YB. Promotion of Sema4D expression by tumor-associated macrophages: Significance in gastric carcinoma. World J Gastroenterol 2018; 24(5): 593-601
URL http://www.wjgnet.com/1007-9327/full/v24/i5/593.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i5.593
Full Article (PDF) WJG-24-593.pdf
Full Article (Word) WJG-24-593.doc
Manuscript File 35979-Review.docx
Answering Reviewers 35979-Answering reviewers.pdf
Audio Core Tip 35979-Audio core tip.m4a
Biostatistics Review Certificate 35979-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 35979-Conflict-of-interest statement.pdf
Copyright License Agreement 35979-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 35979-Institutional-Animal-Care-and-Use-Committee-Statement-revision.pdf
Institutional Review Board Approval Form or Document 35979-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 35979-Language certificate.pdf
Supplementary Material 35979-Supplementary Material.rar
Peer-review Report 35979-Peer-review(s).pdf
Scientific Misconduct Check 35979-Scientific misconduct check.pdf
Scientific Editor Work List 35979-Scientific editor work list.pdf