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Articles Published Processes
1/31/2018 1:17:45 AM | Browse: 938 | Download: 1466
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Received |
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2017-08-26 22:08 |
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Peer-Review Started |
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2017-08-27 02:30 |
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To Make the First Decision |
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2017-09-13 00:54 |
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Return for Revision |
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2017-09-13 02:44 |
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Revised |
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2017-09-26 16:20 |
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Second Decision |
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2017-11-21 11:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-11-21 18:53 |
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Articles in Press |
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2017-11-21 18:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-12-04 01:26 |
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Typeset the Manuscript |
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2018-01-15 08:09 |
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Publish the Manuscript Online |
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2018-01-31 01:17 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Basic Study |
Article Title |
Promotion of Sema4D expression by tumor-associated macrophages: Significance in gastric carcinoma
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Han Li, Jin-Shen Wang, Lin-Jun Mu, Ke-Shu Shan, Le-Ping Li and Yan-Bing Zhou |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Yan-Bing Zhou, PhD, Chief Doctor, Department of Gastrointestinal Surgery, Affilated Hospital of Qingdao University, Qingdao 266071, Shandong Province, China. didi8114@163.com |
Key Words |
Gastric carcinoma; CD68; Semaphorin 4D; Tumor-associated macrophages |
Core Tip |
This study explored the role and clinical significance of semaphorin 4D (Sema4D) expression promoted by tumor-associated macrophages (TAMs) in gastric carcinoma cells. By using immunohistochemical streptavidin-peroxidase method on tissue species and gastric carcinoma cells in non-contact co-culture with human M2 macrophages in vitro, we found that Sema4D protein expression was significantly higher in gastric carcinoma tissues than in adjacent normal tissues, and TAMs promoted the invasion and metastasis of gastric carcinoma cells possibly through upregulated Sema4D protein expression. |
Publish Date |
2018-01-31 01:17 |
Citation |
Li H, Wang JS, Mu LJ, Shan KS, Li LP, Zhou YB. Promotion of Sema4D expression by tumor-associated macrophages: Significance in gastric carcinoma. World J Gastroenterol 2018; 24(5): 593-601 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i5/593.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i5.593 |
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