Publication Name	World Journal of Gastroenterology
Manuscript ID	3614
Country	Japan

Received	2013-05-10 08:09
Peer-Review Started	2013-05-10 20:56
To Make the First Decision	2013-06-09 10:06
Return for Revision	2013-06-20 16:39
Revised	2013-07-08 23:19
Second Decision	2013-08-13 11:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-13 13:48
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-09-12 05:11
Typeset the Manuscript	2013-10-17 15:34
Publish the Manuscript Online	2013-11-08 14:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Rare case of primary choriocarcinoma in the sigmoid colon
Manuscript Source	Invited Manuscript
All Author List	Hiromitsu Maehira, Tomoharu Shimizu, Hiromichi Sonoda, Eiji Mekata, Tomoharo Yamaguchi, Tohru Miyake, Mitsuaki Ishida and Tohru Tani
Funding Agency and Grant Number
Corresponding Author	Tomoharu Shimizu, MD, PhD, Senior Assistant Professor, Department of Surgery, Shiga University of Medical Science, Seta-tsukinowacho, Otsu, Shiga 520-2192, Japan. tomoharu@belle.shiga-med.ac.jp
Key Words	Colon cancer; Colorectal cancer; Chemotherapy; Culture drug sensitivity test; Choriocarcinoma
Core Tip	Primary colorectal choriocarcinoma is an extremely rare neoplasm and is usually associated with a poor prognosis. Only 13 cases of colorectal choriocarcinoma have previously been reported. Systemic chemotherapy is an important prognostic factor in these patients; however, there is no standard chemotherapeutic regimen for this tumor type. We encountered an extremely rare case of choriocarcinoma of the colon which was treated with mFOLFOX6 and bevacizumab based on the results of the culture drug sensitivity test (CD-DST), which suppressed aggressive tumor growth. This suggests that CD-DST may provide, at least in part, therapeutic insight for selecting appropriate antitumor agents for patients with colorectal choriocarcinoma.
Publish Date	2013-11-08 14:06
Citation	Maehira H, Shimizu T, Sonoda H, Mekata E, Yamaguchi T, Miyake T, Ishida M, Tani T. A rare case of primary choriocarcinoma in the sigmoid colon. World J Gastroenterol 2013; 19(39): 6683-6688
URL	http://www.wjgnet.com/1007-9327/full/v19/i39/6683.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i39.6683

Full Article (PDF)	WJG-19-6683.pdf
Manuscript File	3614-Review.doc
Answering Reviewers	3614-Answering reviewers.pdf
Copyright License Agreement	3614-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3614-Language certificate.pdf
Peer-review Report	3614-Peer reviewer(s).pdf
Scientific Editor Work List	3614-Scientific editor work list.doc