Publication Name	World Journal of Biological Chemistry
Manuscript ID	3624
Country	Brazil

Received	2013-05-12 11:34
Peer-Review Started	2013-05-13 10:45
To Make the First Decision	2013-06-09 10:06
Return for Revision	2013-06-20 19:41
Revised	2013-08-01 02:42
Second Decision	2013-10-17 13:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-10-18 06:58
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-10-23 19:17
Typeset the Manuscript	2013-11-26 13:42
Publish the Manuscript Online	2013-12-06 18:20

ISSN	1949-8454 (online)
Open Access
Copyright
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Category	Chemistry, Medicinal
Manuscript Type	Autobiography
Article Title	Changes in aminoacidergic and monoaminergic neurotransmission in the hippocampus and amygdala of rats after ayahuasca ingestion
Manuscript Source	Invited Manuscript
All Author List	Eduardo Ferreira de Castro-Neto, Rafael Henrique da Cunha, Dartiu Xavier da Silveira, Mauricio Yonamine, Telma Luciana Furtado Gouveia, Esper Abrão Cavalheiro, Débora Amado and Maria da Graça Naffah-Mazzacoratti
Funding Agency and Grant Number	Funding Agency Grant Number Fundação de Amparo a Pesquisa do Estado de São Paulo Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Conselho Nacional de Desenvolvimento Científico e Tecnológico Instituto Nacional de Neurociência Translacional
Corresponding Author	Maria da Gra?a Naffah Mazzacoratti, PhD Departamento de Bioquímica, Rua Pedro de Toledo 669, segundo andar, Universidade Federal de S?o Paulo, SP, Brazil 04039032 naffahmazz.nexp@epm.br
Key Words	Ayahuasca; Amino Acids; Monoamines; Hippocampus; Amygdala
Core Tip	Several studies have indicated that the main component of ayahuasca, N,N-dimethyltryptamine (DMT), is structurally similar to serotonin (5-hydroxytryptamine or 5-HT) and also has similarities with lysergic acid and mescaline, normally employed in drug addiction. This infusion contained DMT as a principal ingredient in a psychoactive beverage, used by more than 70 different indigenous groups spread throughout Brazil, Colombia, Peru, Venezuela and Ecuador. In human beings, it is also present in the brain as an endogenous substance and is found in blood, urine and cerebrospinal fluid. After oral administration of ayahuasca at different doses to na?ve rats, we found that ayahuasca ingestion could modify neurotransmitter release in limbic brain structures.
Publish Date	2013-12-06 18:20
Citation	Castro-Neto EF, Cunha RH, Silveira DX, Yonamine M, Gouveia TLF, Cavalheiro EA, Amado D, Naffah-Mazzacoratti MG. Changes in aminoacidergic and monoaminergic neurotransmission in the hippocampus and amygdala of rats after ayahuasca ingestion. World J Biol Chem 2013; 4(4): 141-147
URL	http://www.wjgnet.com/1949-8454/full/v4/i4/141.htm
DOI	http://dx.doi.org/10.4331/wjbc.v4.i4.141

Full Article (PDF)	WJBC-4-141.pdf
Manuscript File	3624-Review.doc
Answering Reviewers	3624-Answering reviewers.pdf
Copyright License Agreement	3624-Copyright assignment.pdf
Peer-review Report	3624-Peer reviewer(s).pdf
Scientific Editor Work List	3624-Scientific editor work list.doc