Publication Name	World Journal of Hepatology
Manuscript ID	36310
Country	Russia

Received	2017-09-19 00:26
Peer-Review Started	2017-09-20 09:23
To Make the First Decision	2017-10-30 06:57
Return for Revision	2017-10-31 06:38
Revised	2017-10-31 14:00
Second Decision	2017-11-23 07:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-02-06 01:43
Articles in Press	2018-02-06 01:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-03-01 11:53
Publish the Manuscript Online	2018-03-04 12:36

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat
Manuscript Source	Invited Manuscript
All Author List	Andrey Elchaninov, Timur Fatkhudinov, Natalia Usman, Irina Arutyunyan, Andrey Makarov, Anastasia Lokhonina, Irina Eremina, Viktor Surovtsev, Dmitry Goldshtein, Galina Bolshakova, Valeria Glinkina and Gennady Sukhikh
ORCID	Author(s) ORCID Number Andrey Elchaninov http://orcid.org/0000-0002-2392-4439 Timur Fatkhudinov http://orcid.org/0000-0002-6498-5764 Natalia Usman http://orcid.org/0000-0002-5999-8843 Irina Arutyunyan http://orcid.org/0000-0002-4344-8943 Andrey Makarov http://orcid.org/0000-0003-2133-2293 Anastasia Lokhonina http://orcid.org/0000-0001-8077-2307 Irina Eremina http://orcid.org/0000-0001-5444-9231 Viktor Surovtsev http://orcid.org/0000-0003-0653-572X Dmitry Goldshtein http://orcid.org/0000-0002-3876-1097 Galina Bolshakova http://orcid.org/0000-0002-9669-0821 Valeria Glinkina http://orcid.org/0000-0001-8708-6940 Gennady Sukhikh http://orcid.org/0000-0003-0214-1213
Funding Agency and Grant Number	Funding Agency Grant Number Russian Science Foundation 17-15-01419
Corresponding Author	Timur Fatkhudinov, DSc, MD, PhD, Academic Research, Laboratory of Regenerative Medicine, National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of Ministry of Healthcare of Russian Federation, 4 Oparina Street, Moscow 117997, Russian Federation, Moscow 117997, Russia. tfat@yandex.ru
Key Words	Liver; Regeneration; Multipotent stromal cells; Macrophages
Core Tip	Umbilical cord-derived multipotent stromal cells stimulate reparative processes within the liver after subtotal resection (removal of 80% of the organ mass). Multipotent stromal cells stimulate hepatocyte proliferation in rats after subtotal resection and favor polarization of macrophages to M2 phenotype. The transplanted MSCs do not differentiate into any of the liver cell types under these conditions.
Publish Date	2018-03-04 12:36
Citation	Elchaninov A, Fatkhudinov T, Usman N, Arutyunyan I, Makarov A, Lokhonina A, Eremina I, Surovtsev V, Goldshtein D, Bolshakova G, Glinkina V, Sukhikh G. Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat. World J Hepatol 2018; 10(2): 287-296
URL	http://www.wjgnet.com/1948-5182/full/v10/i2/287.htm
DOI	http://dx.doi.org/10.4254/wjh.v10.i2.287

Full Article (PDF)	WJH-10-287.pdf
Full Article (Word)	WJH-10-287.doc
Manuscript File	36310-Review.doc
Answering Reviewers	36310-Answering reviewers.pdf
Audio Core Tip	36310-Audio core tip.mp3
Biostatistics Review Certificate	36310-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	36310-Conflict-of-interest statement.pdf
Copyright License Agreement	36310-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	36310-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	36310-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	36310-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	36310-Language certificate.pdf
Peer-review Report	36310-Peer-review(s).pdf
Scientific Misconduct Check	36310-Scientific misconduct check.pdf
Scientific Editor Work List	36310-Scientific editor work list.pdf