Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	36358
Country	Greece

Received	2017-09-21 00:49
Peer-Review Started	2017-09-21 08:07
To Make the First Decision	2017-10-30 07:01
Return for Revision	2017-10-31 06:55
Revised	2017-11-04 23:54
Second Decision	2017-11-23 07:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-12-05 20:04
Articles in Press	2017-12-05 20:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-12-19 08:41
Publish the Manuscript Online	2017-12-27 02:26

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http:///creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Advances and challenges in laparoscopic surgery in the management of hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Ioannis A Ziogas and Georgios Tsoulfas
ORCID	Author(s) ORCID Number Ioannis A Ziogas http://orcid.org/0000-0002-6742-6909 Georgios Tsoulfas http://orcid.org/0000-0001-5043-7962
Funding Agency and Grant Number
Corresponding Author	Georgios Tsoulfas, MD, PhD, 1st Department of Surgery, Aristotle University of Thessaloniki, 66 Tsimiski Street, Thessaloniki 54453, Greece. tsoulfasg@auth.gr
Key Words	Hepatocellular carcinoma; Laparoscopic liver resection; Minimally invasive surgery; Laparoscopic hepatectomy; Liver malignant disease; Surgical excision
Core Tip	Hepatocellular carcinoma is the most common primary malignant tumor of the liver and fifth most common malignancy worldwide. Surgical resection is the therapeutic treatment of choice and its laparoscopic version has come into play since 1992. Several matched comparative studies reported its superiority over open resection regarding operating theatre time and hospital stay, blood loss, need for transfusion and postsurgical opioid analgesics, postoperative pain, morbidity, R0 resection, time to recuperation, time to oral intake and stress response. The high costs of the procedure are offset by the decrease in the length of the operation and hospital stay, while in experienced hands conversion rates and morbidity are even more diminished. Laparoscopic and robotic liver resection is a continuously evolving field of minimally invasive liver surgery with a very promising future.
Publish Date	2017-12-27 02:26
Citation	Ziogas IA, Tsoulfas G. Advances and challenges in laparoscopic surgery in the management of hepatocellular carcinoma. World J Gastrointest Surg 2017; 9(12): 233-245
URL	http://www.wjgnet.com/1948-9366/full/v9/i12/233.htm
DOI	http://dx.doi.org/10.4240/wjgs.v9.i12.233

Full Article (PDF)	WJGS-9-233.pdf
Full Article (Word)	WJGS-9-233.doc
Manuscript File	36358-Review.docx
Answering Reviewers	36358-Answering reviewers.pdf
Audio Core Tip	36358-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	36358-Conflict-of-interest statement.pdf
Copyright License Agreement	36358-Copyright assignment.pdf
Supplementary Material	36358-Supplementary-Material-revision.doc
Peer-review Report	36358-Peer-review(s).pdf
Scientific Misconduct Check	36358-Scientific misconduct check.pdf
Scientific Editor Work List	36358-Scientific editor work list.pdf