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Articles Published Processes
12/20/2017 2:49:19 AM | Browse: 1197 | Download: 1672
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Received |
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2017-09-21 17:13 |
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Peer-Review Started |
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2017-09-22 02:00 |
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To Make the First Decision |
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2017-10-11 01:05 |
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Return for Revision |
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2017-10-12 01:06 |
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Revised |
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2017-10-20 08:59 |
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Second Decision |
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2017-11-14 06:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-11-14 18:59 |
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Articles in Press |
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2017-11-14 18:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-11-20 13:40 |
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Typeset the Manuscript |
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2017-12-06 06:39 |
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Publish the Manuscript Online |
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2017-12-20 02:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Liang Sang, Xue-Mei Wang, Dong-Yang Xu, Li-Xuan Sang, Yan Han and Long-Yang Jiang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xue-Mei Wang, MD, Doctor, Doctor, Department of Ultrasound, The First Hospital of China Medical University, NO. 155 Nanjing North ST., Shenyang 110001, Liaoning Province, China. wangxuemei@cmu1h.com |
| Key Words |
Liver fibrosis; Rat; Morin; Nrf2 |
| Core Tip |
We constructed a liver fibrosis rat model with carbon tetrachloride (CCl4). The Sprague-Dawley rats were randomly divided into four groups: control group, morin group, CCl4 group, and morin + CCl4 group. α-SMA, collagen Ⅰ, collagen Ⅲ, NF-E2-related factor 2 (Nrf2), heme oxygenase (HO-1), and quinone oxidoreductase 1 (NQO1) were analyzed by real-time PCR and Western blot methods using frozen liver specimens. We found that morin could reduce hepatic fibrosis by inducing the expression of Nrf2 and its downstream antioxidant factors in the CCl4-induced rat liver fibrosis model. |
| Publish Date |
2017-12-20 02:49 |
| Citation |
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY. Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model. World J Gastroenterol 2017; 23(47): 8334-8344 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i47/8334.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i47.8334 |
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