Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	36497
Country	United States

Received	2017-10-09 03:56
Peer-Review Started	2017-10-09 08:41
To Make the First Decision	2017-11-03 08:25
Return for Revision	2017-11-03 09:46
Revised	2017-11-10 01:25
Second Decision	2017-11-28 08:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-12-06 01:03
Articles in Press	2017-12-06 01:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-01-02 14:25
Publish the Manuscript Online	2018-01-12 09:26

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Minireviews
Article Title	Vitamin D in esophageal cancer: Is there a role for chemoprevention?
Manuscript Source	Invited Manuscript
All Author List	Carol Rouphael, Afrin Kamal, Madhusudhan R Sanaka and Prashanthi N Thota
ORCID	Author(s) ORCID Number Carol Rouphael http://orcid.org/0000-0003-3492-2073 Afrin Kamal http://orcid.org/0000-0001-8950-8926 Madhusudhan R Sanaka http://orcid.org/0000-0003-2506-8602 Prashanthi N Thota http://orcid.org/0000-0001-7179-4774
Funding Agency and Grant Number
Corresponding Author	Prashanthi N Thota, MD, Department of Gastroenterology and Hepatology, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, United States. thotap@ccf.org
Key Words	Vitamin D; Vitamin D receptor; Esophageal adenocarcinoma; Esophageal squamous cell carcinoma; Genetic polymorphism
Core Tip	Vitamin D has emerged as a promising anti-cancer agent due to its diverse biological effects on tumor differentiation, apoptosis and suppression of cellular proliferation. Ecological studies evaluating exposure to ultraviolet B radiation yielded an inverse correlation with esophageal cancer. When vitamin D dietary intake was assessed, direct association with esophageal cancer was observed. However, circulating 25-hydroxyvitamin D concentrations showed inconsistent results.
Publish Date	2018-01-12 09:26
Citation	Rouphael C, Kamal A, Sanaka MR, Thota PN. Vitamin D in esophageal cancer: Is there a role for chemoprevention? World J Gastrointest Oncol 2018; 10(1): 23-30
URL	http://www.wjgnet.com/1948-5204/full/v10/i1/23.htm
DOI	http://dx.doi.org/10.4251/wjgo.v10.i1.23

Full Article (PDF)	WJGO-10-23.pdf
Full Article (Word)	WJGO-10-23.doc
Manuscript File	36497-Review.docx
Answering Reviewers	36497-Answering reviewers.pdf
Audio Core Tip	36497-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	36497-Conflict-of-interest statement.pdf
Copyright License Agreement	36497-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	36497-Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s).docx
Non-Native Speakers of English Editing Certificate	36497-Non-Native Speakers of English Editing Certificate.docx
Supplementary Material	36497-Supplementary-Material-revision.docx
Peer-review Report	36497-Peer-review(s).pdf
Scientific Misconduct Check	36497-Scientific misconduct check.pdf
Scientific Editor Work List	36497-Scientific editor work list.pdf