Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	3650
Country	United States

Received	2013-05-12 10:59
Peer-Review Started	2013-05-13 09:34
To Make the First Decision	2013-05-23 17:10
Return for Revision	2013-06-05 11:49
Revised	2013-06-08 03:11
Second Decision	2013-06-19 12:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-06-20 01:09
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-06-24 03:28
Typeset the Manuscript	2013-08-05 10:10
Publish the Manuscript Online	2013-08-09 16:10

ISSN	2150-5330 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Why is damage limited to the mucosa in ulcerative colitis but transmural in Crohn’s disease?
Manuscript Source	Invited Manuscript
All Author List	Xiaofa Qin
Funding Agency and Grant Number
Corresponding Author	Xiaofa Qin, MD, PhD, Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, United States. qinxi@umdnj.edu
Key Words	Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Pathogenesis; Neutrophils; Macrophages
Core Tip	In my opinion, ulcerative colitis is more like bacterial pneumonia with the involvement of mainly neutrophils, capacious exudates into the cavity but limited damage of the tissue, while Crohn’s disease is more like pneumoconiosis, such as silicosis or berylliosis, or tuberculosis of the lung with the involvement of mainly macrophages and manifested as granulomatous inflammation in the interstices, destruction of the tissue, extensive proliferation of fibroblasts and formation of fibrosis.
Publish Date	2013-08-09 16:10
Citation	Qin X. Why is damage limited to the mucosa in ulcerative colitis but transmural in Crohn’s disease? World J Gastrointest Pathophysiol 2013; 4(3): 63-64
URL	http://www.wjgnet.com/2150-5330/full/v4/i3/63.htm
DOI	http://dx.doi.org/10.4291/wjgp.v4.i3.63

Full Article (PDF)	WJGP-4-63.pdf
Manuscript File	3650-Review.doc
Answering Reviewers	3650-Answering reviewers.pdf
Copyright License Agreement	3650-Copyright assignment.doc
Peer-review Report	3650-Peer review(s).pdf
Scientific Editor Work List	3650-Scientific editor work list.doc