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1/26/2018 2:31:05 AM | Browse: 1026 | Download: 4558
Publication Name World Journal of Gastroenterology
Manuscript ID 36554
Country/Territory China
Received
2017-10-23 02:39
Peer-Review Started
2017-10-25 01:58
To Make the First Decision
2017-11-15 01:26
Return for Revision
2017-11-17 02:05
Revised
2017-11-23 03:25
Second Decision
2017-11-27 09:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-27 20:11
Articles in Press
2017-11-27 20:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-01-05 04:07
Typeset the Manuscript
2018-01-22 08:51
Publish the Manuscript Online
2018-01-26 02:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil
Manuscript Source Unsolicited Manuscript
All Author List Yan-Shen Kuang, Yi Wang, Li-Dan Ding, Liu Yang, Ying Wang, Si-Han Liu, Bing-Tao Zhu, Xu-Ning Wang, Hong-Yi Liu, Jun Li, Zhi-Jie Chang, Ying-Yin Wang and Bao-Qing Jia
ORCID
Author(s) ORCID Number
Yan-Shen Kuang http://orcid.org/0000-0001-9849-4667
Yi Wang http://orcid.org/0000-0003-4028-2471
Li-Dan Ding http://orcid.org/0000-0003-1094-6775
Liu Yang http://orcid.org/0000-0001-8305-4554
Ying Wang http://orcid.org/0000-0002-0346-376X
Si-Han Liu http://orcid.org/0000-0001-9880-2949
Bing-Tao Zhu http://orcid.org/0000-0003-3356-506X
Xu-Ning Wang http://orcid.org/0000-0002-5979-0508
Hong-Yi Liu http://orcid.org/0000-0002-0903-5205
Jun Li http://orcid.org/0000-0001-7194-1180
Zhi-Jie Chang http://orcid.org/0000-0003-1567-3227
Ying-Yin Wang http://orcid.org/0000-0002-7449-3843
Bao-Qing Jia http://orcid.org/0000-0002-7006-0741
Funding Agency and Grant Number
Funding Agency Grant Number
The Key Project Grant from the National Natural Science Foundation of China 81402293
The Key Project Grant from the National Natural Science Foundation of China 81372372
The Key Project Grant from the National Natural Science Foundation of China 81230044
The National Key Research and Development Program of China 2016YFA0500301
The Key Project Grant from the National Natural Science Foundation of China 81372167
The Key Project Grant from the National Natural Science Foundation of China 81572729
Corresponding Author Bao-Qing Jia, MD, PhD, Chief Doctor, Professor, General Surgery II Department, Chinese PLA General Hospital, 28th FuXing Rd, Haidian Dist., Beijing 100853, China. jiabaoqing@301hospital.com.cn
Key Words CREPT; Colorectal cancer; 5-Fluorouracil; Apoptosis; Cell proliferation
Core Tip Cell cycle-related and expression elevated protein in tumor (CREPT) is an oncogene preferentially expressed in diverse human tumors. Overexpression of CREPT promotes cell proliferation and tumorigenesis. However, the expression and mechanistic involvement of CREPT in colorectal cancer is not fully investigated. Despite tremendous advances in exploitations and clinical applications of 5-Fluorouracil has been achieved in the past decades, drug resistance remains a significant limitation to the clinical use. In another word, the prognostic biomarker for administration of this drug is still in urgent need.
Publish Date 2018-01-26 02:31
Citation Kuang YS, Wang Y, Ding LD, Yang L, Wang Y, Liu SH, Zhu BT, Wang XN, Liu HY, Li J, Chang ZJ, Wang YY, Jia BQ. Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil. World J Gastroenterol 2018; 24(4): 475-483
URL http://www.wjgnet.com/1007-9327/full/v24/i4/475.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i4.475
Full Article (PDF) WJG-24-475.pdf
Full Article (Word) WJG-24-475.doc
Manuscript File 36554-Review.docx
Answering Reviewers 36554-Answering reviewers.pdf
Audio Core Tip 36554-Audio core tip.wav
Biostatistics Review Certificate 36554-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 36554-Conflict-of-interest statement.pdf
Copyright License Agreement 36554-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 36554-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 36554-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 36554-Language certificate.pdf
Peer-review Report 36554-Peer-review(s).pdf
Scientific Misconduct Check 36554-Scientific misconduct check.pdf
Scientific Editor Work List 36554-Scientific editor work list.pdf