Publication Name	World Journal of Hepatology
Manuscript ID	36565
Country	India

Received	2017-10-10 01:36
Peer-Review Started	2017-10-10 09:11
To Make the First Decision	2017-11-07 06:04
Return for Revision	2017-11-07 07:08
Revised	2017-11-08 12:54
Second Decision	2017-11-23 07:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-12-06 05:23
Articles in Press	2017-12-06 05:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-12-22 01:28
Publish the Manuscript Online	2017-12-27 10:31

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Molecular basis of hepatocellular carcinoma induced by hepatitis C virus infection
Manuscript Source	Invited Manuscript
All Author List	Mohammad Irshad, Priyanka Gupta and Khushboo Irshad
ORCID	Author(s) ORCID Number Mohammad Irshad http://orcid.org/0000-0002-0674-3679 Priyanka Gupta http://orcid.org/0000-0001-9813-2260 Khushboo Irshad http://orcid.org/0000-0002-1552-3686
Funding Agency and Grant Number
Corresponding Author	Mohammad Irshad, MAMS, PhD, Professor, Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, PO Box -4938, A I I M S, New Delhi 110029, India. drirshad54@yahoo.com
Key Words	Hepatitis C virus; Hepatocellular carcinoma; Fibrosis; Core; NS5A; Inflammation
Core Tip	Hepatocellular carcinoma (HCC) is one of the most common cancer occurring in human population all over the world. Chronic hepatitis C virus (HCV) infection is considered as a major cause of producing HCC in developed countries. HCV infection induces chronic inflammation in liver, which initiates several changes including production of oxidative stress, steatosis, progressive fibrosis, cirrhosis and finally HCC. HCV related proteins also interact directly with cellular proteins at various steps of cell signaling disturbing cell cycle and regeneration process. HCC is supposed, now days, to be the foremost indication for liver transplant.
Publish Date	2017-12-27 10:31
Citation	Irshad M, Gupta P, Irshad K. Molecular basis of hepatocellular carcinoma induced by hepatitis C virus infection. World J Hepatol 2017; 9(36): 1305-1314 Available from: URL: http://www.wjgnet.com/1948-5182/full/v9/i36/1305.htm DOI: http://dx.doi.org/10.4254/wjh.v9.i36.1305
URL	http://www.wjgnet.com/1948-5182/full/v9/i36/1305.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i36.1305

Full Article (PDF)	WJH-9-1305.pdf
Full Article (Word)	WJH-9-1305.doc
Manuscript File	36565-Review.docx
Answering Reviewers	36565-Answering reviewers.pdf
Audio Core Tip	36565-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	36565-Conflict-of-interest statement.pdf
Copyright License Agreement	36565-Copyright assignment.pdf
Peer-review Report	36565-Peer-review(s).pdf
Scientific Misconduct Check	36565-Scientific misconduct check.pdf
Scientific Editor Work List	36565-Scientific editor work list.pdf