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Articles Published Processes
1/7/2018 4:21:05 AM | Browse: 1407 | Download: 2202
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Received |
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2017-10-09 03:41 |
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Peer-Review Started |
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2017-10-09 08:16 |
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To Make the First Decision |
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2017-10-25 01:03 |
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Return for Revision |
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2017-10-25 09:25 |
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Revised |
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2017-11-13 17:45 |
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Second Decision |
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2017-11-21 12:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-11-21 18:37 |
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Articles in Press |
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2017-11-21 18:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-11-29 20:57 |
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Typeset the Manuscript |
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2017-12-23 15:06 |
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Publish the Manuscript Online |
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2018-01-07 04:21 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Probiotic monotherapy and Helicobacter pylori eradication: A systematic review with pooled-data analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Giuseppe Losurdo, Rossella Cubisino, Michele Barone, Mariabeatrice Principi, Gioacchino Leandro, Enzo Ierardi and Alfredo Di Leo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Enzo Ierardi, MD, Professor, Section of Gastroenterology, Department of Emergency and Organ Transplantation, University “Aldo Moro”, Piazza Giulio Cesare 11, Bari 70124, Italy. e.ierardi@virgilio.it |
| Key Words |
Helicobacter pylori; probiotics; eradication; meta-analysis; breath test |
| Core Tip |
Despite several lines of evidence in the literature having demonstrated a pivotal role of probiotics as adjunctive treatment for Helicobacter pylori (H. pylori) eradication, national and international guidelines do not have a uniform consensus about their clinical application. Many meta-analyses have confirmed that co-administration of probiotics may have a beneficial effect on the prevention of side effects and eradication rates. Herein, we found that probiotic monotherapy may eradicate H. pylori in 14% of cases. Lactobacilli, Saccharomyces boulardii and multistrain combinations eradicated the bacterium with a rate of 16%, 12% and 14%, respectively. Probiotics were significantly more effective than placebo (OR = 7.91). |
| Publish Date |
2018-01-07 04:21 |
| Citation |
Losurdo G, Cubisino R, Barone M, Principi M, Leandro G, Ierardi E, Di Leo A. Probiotic monotherapy and Helicobacter pylori eradication: A systematic review with pooled-data analysis. World J Gastroenterol 2018; 24(1): 139-149 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i1/139.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i1.139 |
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