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Articles Published Processes
1/19/2018 9:46:49 AM | Browse: 1182 | Download: 1627
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Received |
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2017-10-17 02:58 |
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Peer-Review Started |
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2017-10-17 03:21 |
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To Make the First Decision |
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2017-10-31 00:43 |
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Return for Revision |
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2017-11-01 10:09 |
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Revised |
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2017-11-07 04:46 |
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Second Decision |
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2017-11-27 11:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-11-27 20:18 |
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Articles in Press |
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2017-11-27 20:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-12-24 04:45 |
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Typeset the Manuscript |
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2018-01-14 11:48 |
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Publish the Manuscript Online |
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2018-01-19 09:46 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Hypoxia preconditioning protects Ca2+-ATPase activation of intestinal mucosal cells against R/I injury in a rat liver transplantation model
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Peng Ji, Yuan-Xin Li, Bao-Xu Shi, Zhuo-Nan Zhuang, Jing-Yan Yang, Sen Guo, Xiao-Zhou Xu, Ke-Sen Xu and Hai-Lin Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Second Hospital of Shandong University Youth Foundation |
Y2013010033 |
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| Corresponding Author |
Hai-Lin Li, MD, PhD, Adjunct Professor, Department of Hepatobiliary Surgery, The Second Hospital of Shandong University, Shandong University, 247#, Beiyuan Street, Jinan 250033, Shandong Province, China. lehaln01@163.com |
| Key Words |
Hypoxic precondition; Intestinal function; Ischemia/reperfusion; Liver transplantation; Rat |
| Core Tip |
Ischaemia/reperfusion (I/R) injury affects the recovery of postoperative bowel function in liver transplantation. In our research, hypoxia-induced HIF-1α expression could protect mitochondrial function and Ca2+-ATPase activity against I/R injury to reduce the apoptosis and pathological damage to intestinal cells. Therefore, we suggest that hypoxic preconditioning therapy could improve the tolerance of small intestinal mucosal cell to hypoxia in rat autologous orthotopic liver transplantation. |
| Publish Date |
2018-01-19 09:46 |
| Citation |
Ji ZP, Li YX, Shi BX, Zhuang ZN, Yang JY, Guo S, Xu XZ, Xu KS, Li HL. Hypoxia preconditioning protects Ca2+-ATPase activation of intestinal mucosal cells against R/I injury in a rat liver transplantation model. World J Gastroenterol 2018; 24(3): 360-370 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i3/360.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i3.360 |
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