Publication Name	World Journal of Hepatology
Manuscript ID	3666
Country	Greece

Received	2013-05-13 08:54
Peer-Review Started	2013-05-13 09:51
To Make the First Decision	2013-06-09 10:05
Return for Revision	2013-06-20 09:59
Revised	2013-07-20 04:40
Second Decision	2013-09-13 14:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-09-13 22:48
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-23 18:57
Publish the Manuscript Online	2013-10-25 08:47

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Presence of disease specific autoantibodies against liver sinusoidal cells in primary biliary cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Ourania Sfakianaki, Maria Tzardi, Argyro Voumvouraki, Aikaterini Afgoustaki, Meri Koulentaki and Elias Kouroumalis
Funding Agency and Grant Number
Corresponding Author	Elias Kouroumalis, MD, PhD, Professor, Department of Gastroenterology, University Hospital of Heraklion, P.O.BOX 1352, 71100 Heraklion, Crete, Greece. kouroum@ med.uoc.gr
Key Words	Primary biliary cirrhosis; Autoantibodies; Sinusoidal cells; Cholangiocytes; Liver tissue
Core Tip	In this study, indirect immunofluorescence staining was performed on paraffin-embedded human liver sections of various chronic liver diseases to demonstrate the presence of disease specific autoantibodies targeting sinusoidal cells in patient sera. Liver sections from normal and disease controls were used as the substrate, and sera were the source of primary antibodies. Our findings indicate that disease specific antibodies against liver sinusoidal cells circulate in primary biliary cirrhosis (PBC). Various non disease specific antibodies were also found in PBC and chronic hepatitis B but not in other chronic liver diseases.
Publish Date	2013-10-25 08:47
Citation	Sfakianaki O, Tzardi M, Voumvouraki A, Afgoustaki A, Koulentaki M, Kouroumalis E. Presence of disease specific autoantibodies against liver sinusoidal cells in primary biliary cirrhosis. World J Hepatol 2013; 5(10): 568-576
URL	http://www.wjgnet.com/1948-5182/full/v5/i10/568.htm
DOI	http://dx.doi.org/10.4254/wjh.v5.i10.568

Full Article (PDF)	WJH-5-568.pdf
Manuscript File	3666-Review.doc
Answering Reviewers	3666-Answering reviewers.pdf
Copyright License Agreement	3666-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate	3666-Language certificate.pdf
Peer-review Report	3666-Peer reviewer(s).pdf
Scientific Editor Work List	3666-Scientific editor work list.doc