Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	36681
Country	United States

Received	2017-10-16 01:21
Peer-Review Started	2017-10-16 08:48
To Make the First Decision	2017-11-07 06:05
Return for Revision	2017-11-07 07:39
Revised	2017-12-28 15:46
Second Decision	2018-01-08 00:37
Accepted by Journal Editor-in-Chief	2018-01-10 22:06
Accepted by Executive Editor-in-Chief	2018-01-15 20:47
Articles in Press	2018-01-15 20:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-02-03 10:50
Publish the Manuscript Online	2018-02-08 07:50

ISSN	1948-5190 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Utility of endoscopic ultrasound and endoscopy in diagnosis and management of hepatocellular carcinoma and its complications: What does endoscopic ultrasonography offer above and beyond conventional cross-sectional imaging?
Manuscript Source	Invited Manuscript
All Author List	Mohit Girotra, Kaartik Soota, Amaninder S Dhaliwal, Rtika R Abraham, Mauricio Garcia-Saenz-de-Sicilia and Benjamin Tharian
ORCID	Author(s) ORCID Number Mohit Girotra http://orcid.org/0000-0002-7086-7211 Kaartik Soota http://orcid.org/0000-0002-7306-6858 Amaninder S Dhaliwal http://orcid.org/0000-0002-9761-437X Rtika R Abraham http://orcid.org/0000-0002-4608-7899 Mauricio Garcia-Saenz-de-Sicilia http://orcid.org/0000-0003-0886-5175 Benjamin Tharian http://orcid.org/0000-0002-7797-3738
Funding Agency and Grant Number
Corresponding Author	Mohit Girotra, MD, Assistant Professor, Division of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, 1120 NW 14th Street, (D-49) 1111 CRB, Miami, FL 33136, United States. mgirotra@med.miami.edu
Key Words	Hepatocellular carcinoma; Liver; Cancer; Endoscopy; Endoscopic ultrasound; Endoscopic ultrasonography; Fine needle aspiration; Fine needle aspiration; Staging; Treatment; Management
Core Tip	Hepatocellular carcinoma (HCC) constitutes the commonest primary liver cancer, and if diagnosed at an early stage, has better prognosis. Of late, there has been evolution of utility of endoscopic techniques, specifically endoscopic ultrasonography (EUS) with fine needle aspiration, for this purpose. EUS is superior over computed tomography in detecting hepatic lesions smaller than 1cm, and also allows FNA for accurate histopathological diagnosis. This strategy is particularly useful for indeterminate nodules, with non-specific imaging characteristics. Role of EUS in diagnosis and management of HCC are the focus of this article. In addition, other endoscopic techniques, including esophagogastroduodenoscopy and endoscopic retrograde cholangio-pancreatography, are of immense use in management of complications of HCC, which are also briefly discussed in this review.
Publish Date	2018-02-08 07:50
Citation	Girotra M, Soota K, Dhaliwal AS, Abraham RR, Garcia-Saenz-de-Sicilia M, Tharian B. Utility of endoscopic ultrasound and endoscopy in diagnosis and management of hepatocellular carcinoma and its complications: What does endoscopic ultrasonography offer above and beyond conventional cross-sectional imaging? World J Gastrointest Endosc 2018; 10(2): 56-68
URL	http://www.wjgnet.com/1948-5190/full/v10/i2/56.htm
DOI	http://dx.doi.org/10.4253/wjge.v10.i2.56

Full Article (PDF)	WJGE-10-56.pdf
Full Article (Word)	WJGE-10-56.doc
Manuscript File	36681-Review.doc
Answering Reviewers	36681-Answering reviewers.pdf
Audio Core Tip	36681-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	36681-Conflict-of-interest statement.pdf
Copyright License Agreement	36681-Copyright assignment.pdf
Peer-review Report	36681-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	36681-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	36681-Scientific misconduct check.pdf
Scientific Editor Work List	36681-Scientific editor work list.pdf