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Publication Name World Journal of Gastroenterology
Manuscript ID 36697
Country/Territory China
2017-11-05 14:59
Peer-Review Started
2017-11-06 00:50
To Make the First Decision
2017-11-22 01:07
Return for Revision
2017-11-27 04:09
2017-12-03 11:31
Second Decision
2017-12-12 08:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-12 19:43
Articles in Press
2017-12-12 19:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-12-21 11:09
Typeset the Manuscript
2018-01-26 05:56
Publish the Manuscript Online
2018-01-31 01:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research and Experimental
Manuscript Type Basic Study
Article Title Hsa-miR-202-3p, up-regulated in type 1 gastric neuroendocrine neoplasms, may target DUSP1
Manuscript Source Unsolicited Manuscript
All Author List Dou Dou, Yan-Fen Shi, Qing Liu, Jie Luo, Ji-Xi Liu, Meng Liu, Ying-Ying Liu, Yuan-Liang Li, Xu-Dong Qiu and Huang-Ying Tan
Author(s) ORCID Number
Dou Dou http://orcid.org/0000-0002-9443-6731
Yan-Fen Shi http://orcid.org/0000-0001-5348-1205
Qing Liu http://orcid.org/0000-0001-8534-3384
Jie Luo http://orcid.org/0000-0003-2135-8186
Ji-Xi Liu http://orcid.org/0000-0002-2913-848X
Meng Liu http://orcid.org/0000-0002-4555-0490
Ying-Ying Liu http://orcid.org/0000-0001-5966-2605
Yuan-Liang Li http://orcid.org/0000-0003-0774-614X
Xu-Dong Qiu http://orcid.org/0000-0002-9793-3207
Huang-Ying Tan http://orcid.org/0000-0002-6165-5196
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81673763
Corresponding author Huang-Ying Tan, PhD, Professor, Chief Physician, Department of Integrative Oncology, China-Japan Friendship Hospital, No.2 Yinghua street, Beijing 100029, China. tanhuangying@263.net
Keywords microRNA; type 1 g-NEN; neuroendocrine neoplasm; recurrence
Core Tip In this study, we have innovatively used chip technology to study microRNAs in type 1 gastric neuroendocrine neoplasms. We found miR-202-3p was extraordinarily upregulated in the tumours compared to the control samples. Interestingly, although miR-202 belongs to let-7, a famous cancer-suppressing family, some studies have reported its oncogenic potential in some tumours. Then, we found that DUSP1 could be a target gene of miR-202-3p and was closely related to tumour occurrence and development. Finally, we suc­cessfully showed that the miR-202-3p directly regulated DUSP1 in tool cells.
Publish Date 2018-01-31 01:17
Citation Dou D, Shi YF, Liu Q, Luo J, Liu JX, Liu M, Liu YY, Li YL, Qiu XD, Tan HY. Hsa-miR-202-3p, up-regulated in type 1 gastric neuroendocrine neoplasms, may target DUSP1. World J Gastroenterol 2018; 24(5): 573-582
Url http://www.wjgnet.com/1007-9327/full/v24/i5/573.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i5.573
Full Article (PDF) WJG-24-573.pdf
Full Article (Word) WJG-24-573.doc
Manuscript File 36967-Review.docx
Answering Reviewers 36697-Answering reviewers.pdf
Audio Core Tip 36697-Audio core tip.mp3
Biostatistics Review Certificate 36697-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 36697-Conflict-of-interest statement.pdf
Copyright License Agreement 36697-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 36697-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 36697-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 36697-Language certificate.pdf
Peer-review Report 36697-Peer-review(s).pdf
Scientific Misconduct Check 36697-Scientific misconduct check.pdf
Scientific Editor Work List 36697-Scientific editor work list.pdf