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Articles Published Processes
12/20/2017 2:49:19 AM | Browse: 1414 | Download: 1718
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Received |
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2017-10-23 02:39 |
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Peer-Review Started |
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2017-10-25 01:30 |
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To Make the First Decision |
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2017-11-08 03:15 |
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Return for Revision |
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2017-11-09 00:21 |
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Revised |
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2017-11-14 23:21 |
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Second Decision |
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2017-12-04 08:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-12-04 19:58 |
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Articles in Press |
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2017-12-04 19:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-12-13 07:27 |
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Publish the Manuscript Online |
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2017-12-20 02:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Clinical epidemiology and disease burden of nonalcoholic fatty liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Brandon J Perumpail, Muhammad Ali Khan, Eric R Yoo, George Cholankeril, Donghee Kim and Aijaz Ahmed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Aijaz Ahmed, MD, Associate Professor, Attending Doctor, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 750 Welch Road, Suite # 210, Palo Alto, CA 94304, United States. aijazahmed@stanford.edu |
| Key Words |
Nonalcoholic fatty liver disease; Hepatic steatosis; Fatty liver; Prevalence; Incidence; Fibrosis; Risk factor; Epidemiology; Outcomes; Nonalcoholic steatohepatitis |
| Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is a term for a host of histological findings stemming from hepatic steatosis and remains the most common liver disease globally with increasing prevalence. The vast variation in disease presentation complicates diagnosis, leading to an underestimate of actual disease occurrence. NAFLD is associated with many metabolic comorbidities, including obesity, type Ⅱ diabetes, dyslipidemia, and metabolic syndrome. Its potential to develop into more severe liver conditions, such as nonalcoholic steatohepatitis, advanced fibrosis, cirrhosis and hepatocellular carcinoma, can lead to a state in which liver transplantation is the only treatment option available. The population at risk of developing progressive liver disease creates a challenge to the healthcare system in terms of screening for this evolving epidemic of liver disease. |
| Publish Date |
2017-12-20 02:49 |
| Citation |
Perumpail BJ, Khan MA, Yoo ER, Cholankeril G, Kim D, Ahmed A. Clinical epidemiology and disease burden of nonalcoholic fatty liver disease. World J Gastroenterol 2017; 23(47): 8263-8276 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i47/8263.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i47.8263 |
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