Publication Name	World Journal of Gastroenterology
Manuscript ID	36845
Country	Italy

Received	2017-10-27 00:33
Peer-Review Started	2017-10-27 08:07
To Make the First Decision	2017-11-22 00:58
Return for Revision	2017-11-27 09:22
Revised	2017-12-16 08:23
Second Decision	2017-12-19 11:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-12-20 02:21
Articles in Press	2017-12-20 02:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-01-08 07:29
Publish the Manuscript Online	2018-01-14 05:07

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Drug-eluting beads transarterial chemoembolization for hepatocellular carcinoma: Current state of the art
Manuscript Source	Invited Manuscript
All Author List	Antonio Facciorusso
ORCID	Author(s) ORCID Number Antonio Facciorusso http://orcid.org/0000-0002-2107-2156
Funding Agency and Grant Number
Corresponding Author	Antonio Facciorusso, MD, PhD, Assistant Professor, Gastroenterology Unit, Department of Medical Sciences, University of Foggia, Viale L.Pinto 1, Foggia 71122, Italy. antonio.facciorusso@virgilio.it
Key Words	Embolization; Doxorubicin; Conventional; Hepatocarcinoma; Liver cancer; Survival
Core Tip	Aim of this review is to summarize the main characteristics and the clinical results of drug-eluting beads (DEB)-transarterial chemoembolization (TACE). To obviate to the limitations of cTACE, non-absorbable embolic microspheres charged with cytotoxic agents (DEBs) have been developed. DEBs are able to simultaneously exert both the therapeutic components of TACE, either drug-carrier function and embolization. This way, risk of systemic drug release is minimal. However, despite promising results of preliminary studies, clear evidence of superiority of DEB-TACE over cTACE is still lacking. In absence of well-designed randomized-controlled trials, the decision on whether use DEB-TACE or cTACE is still controversial.
Publish Date	2018-01-14 05:07
Citation	Facciorusso A. Drug-eluting beads transarterial chemoembolization for hepatocellular carcinoma: Current state of the art. World J Gastroenterol 2018; 24(2): 161-169
URL	http://www.wjgnet.com/1007-9327/full/v24/i2/161.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i2.161

Full Article (PDF)	WJG-24-161.pdf
Full Article (Word)	WJG-24-161.doc
Manuscript File	36845-Review.docx
Answering Reviewers	36845-Answering reviewers.pdf
Audio Core Tip	36845-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	36845-Conflict-of-interest statement.pdf
Copyright License Agreement	36845-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	36845-Language certificate.pdf
Peer-review Report	36845-Peer-review(s).pdf
Scientific Misconduct Check	36845-Scientific misconduct check.pdf
Scientific Editor Work List	36845-Scientific editor work list.pdf